Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


CT colonoscopy has 90 percent agreement rate with optical colonoscopy

Nearly 90% of colon polyps greater than or equal to 6 mm in size detected at CT colonoscopy were demonstrated to represent true polyps at subsequent optical colonoscopy (the traditional method of viewing the colon and removing precancerous growths), according to a new study by researchers from the University of Wisconsin Hospital and Clinics in Madison, WI.

"We analyzed the findings of 363 CTC-detected lesions in 244 patients who subsequently underwent optical colonoscopy," said Tyler Prout, MD, lead author of the study. The researchers found that optical colonoscopy verified the presence of polyps in 321 of the 363 CTC-detected instances, making for an overall positive predictive value of 88.4%, he said. In addition, the combined group of polyps with either sessile or pedunculated morphology yielded a matching lesion at optical colonoscopy 91.8% of the time, Dr. Prout added.

"From a practical standpoint, this is very important, because if CTC is to be an effective screening tool it, must not only have a high sensitivity, but have sufficiently high concordance rate at subsequent optical colonoscopy to avoid unnecessary colonoscopies," said Dr. Prout.

Exact polyp size had little effect on the concordance rate, said Dr. Prout. "In our more recent experience, we do nearly as well detecting the smaller 6-7 mm polyps as those that are 1 cm or greater. Moreover, when comparing these results to our earlier experience, we find our positive predictive value at the 6-7mm polyp size threshold to be much improved; now 85%, whereas it was previously just over 50%," said Dr. Prout. "We believe that this finding can be attributed to a combination of factors, some of the most important of which include colonic preparation and method of image analysis. Our colonic preparation includes both fluid and stool tagging. For image analysis, we employ a primary 3D evaluation complemented by focused review of 2D multiplanar reformats for confirmation. This is in contradistinction from many studies that utilize primary 2D interpretation," said Dr. Prout.

The full results of this study will be presented as an electronic exhibit Monday, May 7 through Thursday May 10 during the American Roentgen Ray Society’s annual meeting in Orlando, FL.

Necoya Lightsey | EurekAlert!
Further information:

More articles from Medical Engineering:

nachricht Gentle sensors for diagnosing brain disorders
29.09.2016 | King Abdullah University of Science and Technology

nachricht New imaging technique in Alzheimer’s disease - opens up possibilities for new drug development
28.09.2016 | Lund University

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Greater Range and Longer Lifetime

26.10.2016 | Power and Electrical Engineering

VDI presents International Bionic Award of the Schauenburg Foundation

26.10.2016 | Awards Funding

3-D-printed magnets

26.10.2016 | Power and Electrical Engineering

More VideoLinks >>>