"We analyzed the findings of 363 CTC-detected lesions in 244 patients who subsequently underwent optical colonoscopy," said Tyler Prout, MD, lead author of the study. The researchers found that optical colonoscopy verified the presence of polyps in 321 of the 363 CTC-detected instances, making for an overall positive predictive value of 88.4%, he said. In addition, the combined group of polyps with either sessile or pedunculated morphology yielded a matching lesion at optical colonoscopy 91.8% of the time, Dr. Prout added.
"From a practical standpoint, this is very important, because if CTC is to be an effective screening tool it, must not only have a high sensitivity, but have sufficiently high concordance rate at subsequent optical colonoscopy to avoid unnecessary colonoscopies," said Dr. Prout.
Exact polyp size had little effect on the concordance rate, said Dr. Prout. "In our more recent experience, we do nearly as well detecting the smaller 6-7 mm polyps as those that are 1 cm or greater. Moreover, when comparing these results to our earlier experience, we find our positive predictive value at the 6-7mm polyp size threshold to be much improved; now 85%, whereas it was previously just over 50%," said Dr. Prout. "We believe that this finding can be attributed to a combination of factors, some of the most important of which include colonic preparation and method of image analysis. Our colonic preparation includes both fluid and stool tagging. For image analysis, we employ a primary 3D evaluation complemented by focused review of 2D multiplanar reformats for confirmation. This is in contradistinction from many studies that utilize primary 2D interpretation," said Dr. Prout.
The full results of this study will be presented as an electronic exhibit Monday, May 7 through Thursday May 10 during the American Roentgen Ray Society’s annual meeting in Orlando, FL.
Necoya Lightsey | EurekAlert!
Rutgers researchers develop automated robotic device for faster blood testing
14.06.2018 | Rutgers University
Speech comprehension with a cochlear implant
04.06.2018 | Universität zu Lübeck
In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...
Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
13.06.2018 | Event News
08.06.2018 | Event News
05.06.2018 | Event News
21.06.2018 | Earth Sciences
21.06.2018 | Life Sciences
21.06.2018 | Earth Sciences