Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

CT colonoscopy has 90 percent agreement rate with optical colonoscopy

07.05.2007
Nearly 90% of colon polyps greater than or equal to 6 mm in size detected at CT colonoscopy were demonstrated to represent true polyps at subsequent optical colonoscopy (the traditional method of viewing the colon and removing precancerous growths), according to a new study by researchers from the University of Wisconsin Hospital and Clinics in Madison, WI.

"We analyzed the findings of 363 CTC-detected lesions in 244 patients who subsequently underwent optical colonoscopy," said Tyler Prout, MD, lead author of the study. The researchers found that optical colonoscopy verified the presence of polyps in 321 of the 363 CTC-detected instances, making for an overall positive predictive value of 88.4%, he said. In addition, the combined group of polyps with either sessile or pedunculated morphology yielded a matching lesion at optical colonoscopy 91.8% of the time, Dr. Prout added.

"From a practical standpoint, this is very important, because if CTC is to be an effective screening tool it, must not only have a high sensitivity, but have sufficiently high concordance rate at subsequent optical colonoscopy to avoid unnecessary colonoscopies," said Dr. Prout.

Exact polyp size had little effect on the concordance rate, said Dr. Prout. "In our more recent experience, we do nearly as well detecting the smaller 6-7 mm polyps as those that are 1 cm or greater. Moreover, when comparing these results to our earlier experience, we find our positive predictive value at the 6-7mm polyp size threshold to be much improved; now 85%, whereas it was previously just over 50%," said Dr. Prout. "We believe that this finding can be attributed to a combination of factors, some of the most important of which include colonic preparation and method of image analysis. Our colonic preparation includes both fluid and stool tagging. For image analysis, we employ a primary 3D evaluation complemented by focused review of 2D multiplanar reformats for confirmation. This is in contradistinction from many studies that utilize primary 2D interpretation," said Dr. Prout.

The full results of this study will be presented as an electronic exhibit Monday, May 7 through Thursday May 10 during the American Roentgen Ray Society’s annual meeting in Orlando, FL.

Necoya Lightsey | EurekAlert!
Further information:
http://www.arrs.org

More articles from Medical Engineering:

nachricht Novel PET imaging agent could help guide therapy for brain diseases
03.04.2018 | Society of Nuclear Medicine and Molecular Imaging

nachricht New Computer Architecture: Time Lapse for Dementia Research
29.03.2018 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: BAM@Hannover Messe: innovative 3D printing method for space flight

At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.

Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...

Im Focus: Molecules Brilliantly Illuminated

Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.

Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...

Im Focus: Spider silk key to new bone-fixing composite

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Quantum Technology for Advanced Imaging – QUILT

24.04.2018 | Information Technology

AWI researchers measure a record concentration of microplastic in arctic sea ice

24.04.2018 | Earth Sciences

Complete skin regeneration system of fish unraveled

24.04.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>