The research will be presented at the Conference on Lasers and Electro-Optics and the Quantum Electronics and Laser Science Conference in Baltimore on May 10.
The new imaging system is based on Optical Coherence Tomography (OCT), which uses light to obtain high-resolution, cross-sectional images of the eye to visualize subtle changes that occur in retinal disease. OCT was developed in the early 1990s by MIT Professor James Fujimoto, Eric Swanson at MIT Lincoln Laboratory and collaborators; Fujimoto is an author of the report to be presented in May.
"Within the last few years optical coherence tomography has become a standard diagnostic for ophthalmology. New techniques are now enabling dramatic increases in image acquisition speeds. These advances promise to enable new and powerful three-dimensional visualization methods which could improve early diagnosis of disease and treatment monitoring," said Fujimoto, who holds appointments in MIT's Department of Electrical Engineering and Computer Science and the Research Laboratory of Electronics.
Conventional OCT imaging typically yields a series of two-dimensional cross-sectional images of the retina, which can be combined to form a 3-D image of its volume. The system works by scanning light back and forth across the eye, measuring the echo time delay of reflected light along micrometer-scale lines that, row by row, build up high-resolution images.
Commercial OCT systems scan the eye at rates ranging from several hundred to several thousand lines per second. But a typical patient can only keep the eye still for about one second, limiting the amount of three-dimensional data that can be acquired.
Now, using the new laser, researchers in Fujimoto's group report retinal scans at record speeds of up to 236,000 lines per second, a factor of 10 improvement over current OCT technology.
Future clinical studies, as well as further development, may someday enable ophthalmologists to routinely obtain three-dimensional "OCT snapshots" of the eye, containing comprehensive volumetric information about the microstructure of the retina. Such snapshots could potentially improve diagnoses of retinal diseases such as diabetic retinopathy, glaucoma and age-related macular degeneration.
Fujimoto's colleagues on the work are Robert Huber, a visiting scientist at MIT now at the Ludwig-Maximilians University in Germany, Desmond C. Adler and Vivek Srinivasan. Adler and Srinivasan are both graduate students in EECS.
The current research was sponsored by the National Science Foundation, the National Institutes of Health and the Air Force Office of Scientific Research.
Elizabeth A. Thomson | MIT News Office
Gentle sensors for diagnosing brain disorders
29.09.2016 | King Abdullah University of Science and Technology
New imaging technique in Alzheimer’s disease - opens up possibilities for new drug development
28.09.2016 | Lund University
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences