Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Natural chemistry finds its way to market

14.11.2005


Faster reaction rates, a substantially higher yield and a cleaner production process than is currently possible in the chemical industry. That is the result of a new sustainable chemical process that researchers from Universiteit van Amsterdam and Radboud Universiteit Nijmegen have developed with support from NWO ACTS (Advanced Chemical Technologies for Sustainability). A patent has recently been requested for this discovery.



Faster reaction rates, a substantially higher yield and a cleaner production process than is currently possible in the chemical industry. That is the result of a new sustainable chemical process that researchers from Universiteit van Amsterdam and Radboud Universiteit Nijmegen have developed with support from NWO ACTS (Advanced Chemical Technologies for Sustainability). A patent has recently been requested for this discovery.

The researchers discovered a so-called one-pot synthesis of complex molecules, in which several chemical steps take place in a single reaction vessel. Such an approach is very common in nature, for example, the life processes in a cell. However, in the laboratory and the chemical industry it is still in its infancy. The industrial partner of the researchers, Synthon, has recently requested a patent for this discovery. This is the first patent to emerge from an ACTS research project.


In the synthesis, the researchers combined a chemical reaction step, a metal-catalysed conversion, with a biological step that uses enzymes. For this to work the reaction conditions, e.g. temperature and pH, must be optimised for both steps. To their surprise the researchers noted that the resulting one-pot synthesis eventually lead to faster reaction rates with a substantially higher yield, than the two separate reactions.

Medicines

This synthesis concerns products built from complex molecules, for example, drug molecules. The pharmaceutical industry is particularly interested in such innovative methods. As well as economic benefits, these all provide advantages in the area of sustainability: a reduction in the number of reaction steps leads to a reduction in waste substances and a reduction in the energy needed.

The research project is one of nine projects currently running within the ACTS programme IBOS (Integration of Biosynthesis and Organic Synthesis). The cooperating partners in this project are Universiteit van Amsterdam, Radboud Universiteit Nijmegen, Technische Universiteit Eindhoven and the pharmaceutical company Synthon. The IBOS programme is one of the five subsidy programmes supported by ACTS.

Dr Maarten de Zwart | alfa
Further information:
http://www.nwo.nl/nwohome.nsf/pages/NWOP_6HQCFM_Eng

More articles from Life Sciences:

nachricht A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>