New study shows animals experience severe stress response at slightest contact with researchers
Mice, rabbits, rats, beagles, geese, and other animals all show measurable physiological stress responses to routine laboratory procedures that have been up until now viewed as relatively benign. The findings come in a new report published in Contemporary Topics in Laboratory Animal Science, based on an extensive review of the scientific literature by ethologist Jonathan Balcombe, Ph.D., of Physicians Committee for Responsible Medicine (PCRM). For example, a mouse who is picked up and briefly held experiences several physiological reactions. As stress-response hormones flood the bloodstream, the mouse exhibits a racing pulse and a spike in blood pressure. These symptoms can persist for up to an hour after each event. Immune response is also affected. In rats and mice, the growth of tumors is strongly influenced by how much the animals are handled. Dr. Balcombe’s paper appears in the journal’s current issue, Autumn 2004, available mid-December.
Until now, humane concerns focused mainly on the experiments themselves. The new findings suggest that routine procedures, such as blood draws and use of stomach tubes, are terrifying for animals. "In essence, there is no such thing as a humane animal experiment," says Dr. Balcombe. "Fear or panic ensues when the animal is touched or stuck with a needle."
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