Defeating high blood pressure may be a matter of a little molecular manipulation.
Some drugs for hypertension, such as so-called ACE inhibitors, block specific receptor proteins on the cell. But researchers at Jefferson Medical College instead have looked to a certain molecular pathway called the Gq signaling pathway, showing that it plays an important role in developing various models of hypertension. The work might lead to new insights into the roots of hypertension, and eventually, the scientists believe, novel therapies.
Andrea Eckhart, Ph.D., associate professor of medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia and her co-workers focused on drugs known as alpha-adrenergic receptor blockers and angiotensin II receptor blockers (including ACE inhibitors), which block angiotensin over-production, and which can lead to high blood pressure. Both of these receptors normally bind to a class of receptors called Gq, which ultimately leads to hypertension.
Steve Benowitz | EurekAlert!
Cancer diagnosis: no more needles?
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The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.
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A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
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At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
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There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
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