In an effort that may someday lead to the treatment of hearing loss and balance disorders, which currently affect about 28 million Americans, Marine Biological Laboratory (MBL) visiting investigators Jeffrey Corwin and Stefan Heller are working this summer to make large numbers of mouse stem cells "grow" into inner ear sensory hair cells-acoustic receptors that are a critical part of the auditory system.
The work is important because, in humans, inner ear sensory hair cells are a precious commodity. Humans are born with only about sixteen thousand of these sound detectors in each ear, which can be easily damaged by age, certain illnesses, exposure to loud sounds, and some medications. Once damaged, the cells do not easily grow back. And with the cell loss comes so-called irreversible hearing loss.
The two scientists are collaborating to develop new methods to expand and maintain adult stem cells isolated from the mouse inner ear to establish long-term stable cell lines. This is the first step toward the ultimate goal of creating implantable human hair cells that will grow happily; eventually repairing damaged hearing and restoring balance.
Molecular Force Sensors
20.09.2017 | Max-Planck-Institut für Biochemie
Foster tadpoles trigger parental instinct in poison frogs
20.09.2017 | Veterinärmedizinische Universität Wien
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
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