Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Gene determines rapidity of ejaculation in men

The rapidity of ejaculation in men is genetically determined. This is the result of research by Utrecht University. Neuropsychiatrist Dr Marcel Waldinger and Pharmacological Researcher Paddy Janssen studied 89 Dutch men with premature ejaculation and will publish the results this week in the renowned International scientific journal the Journal of Sexual Medicine.

The participants in the study by Waldinger and Janssen were 89 Dutch men who suffer from the primary form of premature ejaculation, in other words, men who always had this problem. A control group of 92 men was also studied. For a month the female partners used a stopwatch at home to measure the time until ejaculation each time they had intercourse. ‘This study applies to men who have always ejaculated prematurely from their first sexual contact onwards and not for men who started suffering from this later on in life,’ Waldinger emphasises.

Serotonin deficiency
In men who suffer from premature ejaculation, the substance serotonin appears to be less active between the nerves in the section of the brain that controls the ejaculation. Among other things, this substance is linked to sexual activity and appetite. It is a substance that transfers a signal from one neuron to another. Due to the low activity of serotonin, this signal transfer does not occur properly in men with the primary form of premature ejaculation.
Gene responsible
A gene which had already been discovered, namely 5-HTTLPR, appears to be responsible for the amount and activity of serotonin, which means that it controls the rapidity of ejaculation. Three types of the gene exist: LL, SL and SS. The study showed that the LL type causes a more rapid ejaculation. On average, men with LL ejaculate twice as quickly as men with SS, and also almost twice as quickly as men with SL. The researchers are currently also looking for other genes that are involved in ejaculation.
Not psychological
As long ago as 1998, researcher Marcel Waldinger predicted that both the rapidity with which men ejaculate and the primary form of premature ejaculation were genetically determined. ‘This theory contradicts the idea, which has been common for years, that the primary form of premature ejaculation is a psychological disorder,’ explains Waldinger. ‘The results of our research confirm the genetic theory and may contribute to possible gene therapy against premature ejaculation.’
P.K.C. Janssen, M.D. Waldinger and others. Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism is Associated with the Intravaginal Ejaculation Latency Time in Dutch Men with Lifelong Premature Ejaculation, Journal of Sexual Medicine, October 7, 2008, e-pub. Dr Marcel Waldinger is a neuropsychiatrist at the Leyenburg site of the HagaZiekenhuis in The Hague and is associate professor of Sexual Psychopharmacology at Utrecht University. Paddy Janssen is a pharmacological researcher at Utrecht University. The article will appear online later this week and will then be available to journalists. Please send an e-mail to

Peter van der Wilt | alfa
Further information:

More articles from Life Sciences:

nachricht Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München

nachricht Second research flight into zero gravity
21.10.2016 | Universität Zürich

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Novel mechanisms of action discovered for the skin cancer medication Imiquimod

21.10.2016 | Life Sciences

Second research flight into zero gravity

21.10.2016 | Life Sciences

How Does Friendly Fire Happen in the Pancreas?

21.10.2016 | Life Sciences

More VideoLinks >>>