Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

World Health Summit: Instantaneous Genome Analysis presented by Hasso Plattner Institute

19.10.2012
A new database technology from Hasso Plattner Institute (HPI) holds the promise of utilizing personalized medicine on a comprehensive scale. This technology is to be presented at the World Health Summit on October 24th in Berlin.
Originally developed for corporate software and honored with the 2012 German Innovation prize, In-Memory Technology will also help in the future to analyze and evaluate huge amounts of medical data in real-time. Complicated and expensive treatments, such as those for cancer patients, could then be carried out faster and better tailored to fit each patient.

"Personalized medicine aims to base treatment decisions on all patient-specific information. To be able to do this in the future increasingly more data must be processed during the treatment and, for instance, the 'construction plan' of every single person - the DNA, must be examined for genetic changes,” said the director of HPI Prof. Christoph Meinel. According to the computer scientist, this entails huge amounts of data since every human being carries around approximately 3.2 billion pieces of genetic information.
Researchers led by Dr. Matthieu-Patrick Schapranow, from the chair of HPI founder Prof. Hasso Plattner, tackle the huge mountain of data with a 1,000 core high-performance computer cluster - one of the three of this kind worldwide. “To analyze genetic changes in real-time, we combine the research results of global medical research databases into a knowledge base at HPI. High-performance computing combined with huge main-memory capacities help us to identify genetic dispositions and treatment-relevant supplementary information interactively within seconds, instead of determining it manually over a period of days,” said Schapranow, who works closely with the Charité university hospital. The result: the instantaneous analysis of genome data via a cloud application.

Until now, physicians and researcher had to spend weeks of their valuable time researching medical literature and latest medical research results on the Internet. Thanks to the HPI technology, genome data analysis now takes only a few seconds. If mutations are discovered with relevance to the illness, the technology saves the oncologist many laborious individual queries in scientific databases. Instead, the results are sorted automatically according to their relevance and in comparison to all internationally-known research results. In this way, the most current knowledge about an illness can always be incorporated into its treatment.

Additionally, doctors get decisive supplementary information in the genome browser of HPI about every mutation displayed in terms of its frequency, related diseases, pharmacological relationships, possible active substances, as well as clinical studies that allow a more specific treatment.

Profile of the Hasso-Plattner-Institute

The Hasso Plattner Institute for Software Systems Engineering GmbH (HPI) in Potsdam is Germany’s university excellence center for IT Systems Engineering. It is the only university institution in Germany offering bachelor and master programs in “IT Systems Engineering” – a practical and engineering-oriented course of studies in computer science, in which currently 460 students are enrolled. The HPI School of Design Thinking is Europe’s first innovation school and is based on the Stanford d.school model. It offers 120 places for a supplementary study. There are a total of ten HPI professors and a further 50 guest professors, lecturers and contract teachers at the Institute. HPI carries out research noted for its standard of excellence in its nine topic areas, as well as in the HPI Research School for PhD candidates, with its further research branches in Cape Town, Haifa and Nanjing. HPI teaching and research focuses on the foundation and application of large-scale, highly complex and interconnected IT systems. The development and exploration of user-driven innovations for every part of life is an additional area of emphasis. HPI always earns the highest positions in the CHE university ranking. Since the beginning of September the Institute has offered http://www.openHPI.de, an interactive Internet educational network that is open to everyone.

Hans-Joachim Allgaier | idw
Further information:
http://www.hpi.uni-potsdam.de/
http://epic.hpi.uni-potsdam.de/Home/HigProject

More articles from Information Technology:

nachricht Information integration and artificial intelligence for better diagnosis and therapy decisions
24.05.2017 | Fraunhofer MEVIS - Institut für Bildgestützte Medizin

nachricht World's thinnest hologram paves path to new 3-D world
18.05.2017 | RMIT University

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>