Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

World Health Summit: Instantaneous Genome Analysis presented by Hasso Plattner Institute

19.10.2012
A new database technology from Hasso Plattner Institute (HPI) holds the promise of utilizing personalized medicine on a comprehensive scale. This technology is to be presented at the World Health Summit on October 24th in Berlin.
Originally developed for corporate software and honored with the 2012 German Innovation prize, In-Memory Technology will also help in the future to analyze and evaluate huge amounts of medical data in real-time. Complicated and expensive treatments, such as those for cancer patients, could then be carried out faster and better tailored to fit each patient.

"Personalized medicine aims to base treatment decisions on all patient-specific information. To be able to do this in the future increasingly more data must be processed during the treatment and, for instance, the 'construction plan' of every single person - the DNA, must be examined for genetic changes,” said the director of HPI Prof. Christoph Meinel. According to the computer scientist, this entails huge amounts of data since every human being carries around approximately 3.2 billion pieces of genetic information.
Researchers led by Dr. Matthieu-Patrick Schapranow, from the chair of HPI founder Prof. Hasso Plattner, tackle the huge mountain of data with a 1,000 core high-performance computer cluster - one of the three of this kind worldwide. “To analyze genetic changes in real-time, we combine the research results of global medical research databases into a knowledge base at HPI. High-performance computing combined with huge main-memory capacities help us to identify genetic dispositions and treatment-relevant supplementary information interactively within seconds, instead of determining it manually over a period of days,” said Schapranow, who works closely with the Charité university hospital. The result: the instantaneous analysis of genome data via a cloud application.

Until now, physicians and researcher had to spend weeks of their valuable time researching medical literature and latest medical research results on the Internet. Thanks to the HPI technology, genome data analysis now takes only a few seconds. If mutations are discovered with relevance to the illness, the technology saves the oncologist many laborious individual queries in scientific databases. Instead, the results are sorted automatically according to their relevance and in comparison to all internationally-known research results. In this way, the most current knowledge about an illness can always be incorporated into its treatment.

Additionally, doctors get decisive supplementary information in the genome browser of HPI about every mutation displayed in terms of its frequency, related diseases, pharmacological relationships, possible active substances, as well as clinical studies that allow a more specific treatment.

Profile of the Hasso-Plattner-Institute

The Hasso Plattner Institute for Software Systems Engineering GmbH (HPI) in Potsdam is Germany’s university excellence center for IT Systems Engineering. It is the only university institution in Germany offering bachelor and master programs in “IT Systems Engineering” – a practical and engineering-oriented course of studies in computer science, in which currently 460 students are enrolled. The HPI School of Design Thinking is Europe’s first innovation school and is based on the Stanford d.school model. It offers 120 places for a supplementary study. There are a total of ten HPI professors and a further 50 guest professors, lecturers and contract teachers at the Institute. HPI carries out research noted for its standard of excellence in its nine topic areas, as well as in the HPI Research School for PhD candidates, with its further research branches in Cape Town, Haifa and Nanjing. HPI teaching and research focuses on the foundation and application of large-scale, highly complex and interconnected IT systems. The development and exploration of user-driven innovations for every part of life is an additional area of emphasis. HPI always earns the highest positions in the CHE university ranking. Since the beginning of September the Institute has offered http://www.openHPI.de, an interactive Internet educational network that is open to everyone.

Hans-Joachim Allgaier | idw
Further information:
http://www.hpi.uni-potsdam.de/
http://epic.hpi.uni-potsdam.de/Home/HigProject

More articles from Information Technology:

nachricht Deep Learning predicts hematopoietic stem cell development
21.02.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Sensors embedded in sports equipment could provide real-time analytics to your smartphone
16.02.2017 | University of Illinois College of Engineering

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>