Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


World Health Summit: Instantaneous Genome Analysis presented by Hasso Plattner Institute

A new database technology from Hasso Plattner Institute (HPI) holds the promise of utilizing personalized medicine on a comprehensive scale. This technology is to be presented at the World Health Summit on October 24th in Berlin.
Originally developed for corporate software and honored with the 2012 German Innovation prize, In-Memory Technology will also help in the future to analyze and evaluate huge amounts of medical data in real-time. Complicated and expensive treatments, such as those for cancer patients, could then be carried out faster and better tailored to fit each patient.

"Personalized medicine aims to base treatment decisions on all patient-specific information. To be able to do this in the future increasingly more data must be processed during the treatment and, for instance, the 'construction plan' of every single person - the DNA, must be examined for genetic changes,” said the director of HPI Prof. Christoph Meinel. According to the computer scientist, this entails huge amounts of data since every human being carries around approximately 3.2 billion pieces of genetic information.
Researchers led by Dr. Matthieu-Patrick Schapranow, from the chair of HPI founder Prof. Hasso Plattner, tackle the huge mountain of data with a 1,000 core high-performance computer cluster - one of the three of this kind worldwide. “To analyze genetic changes in real-time, we combine the research results of global medical research databases into a knowledge base at HPI. High-performance computing combined with huge main-memory capacities help us to identify genetic dispositions and treatment-relevant supplementary information interactively within seconds, instead of determining it manually over a period of days,” said Schapranow, who works closely with the Charité university hospital. The result: the instantaneous analysis of genome data via a cloud application.

Until now, physicians and researcher had to spend weeks of their valuable time researching medical literature and latest medical research results on the Internet. Thanks to the HPI technology, genome data analysis now takes only a few seconds. If mutations are discovered with relevance to the illness, the technology saves the oncologist many laborious individual queries in scientific databases. Instead, the results are sorted automatically according to their relevance and in comparison to all internationally-known research results. In this way, the most current knowledge about an illness can always be incorporated into its treatment.

Additionally, doctors get decisive supplementary information in the genome browser of HPI about every mutation displayed in terms of its frequency, related diseases, pharmacological relationships, possible active substances, as well as clinical studies that allow a more specific treatment.

Profile of the Hasso-Plattner-Institute

The Hasso Plattner Institute for Software Systems Engineering GmbH (HPI) in Potsdam is Germany’s university excellence center for IT Systems Engineering. It is the only university institution in Germany offering bachelor and master programs in “IT Systems Engineering” – a practical and engineering-oriented course of studies in computer science, in which currently 460 students are enrolled. The HPI School of Design Thinking is Europe’s first innovation school and is based on the Stanford model. It offers 120 places for a supplementary study. There are a total of ten HPI professors and a further 50 guest professors, lecturers and contract teachers at the Institute. HPI carries out research noted for its standard of excellence in its nine topic areas, as well as in the HPI Research School for PhD candidates, with its further research branches in Cape Town, Haifa and Nanjing. HPI teaching and research focuses on the foundation and application of large-scale, highly complex and interconnected IT systems. The development and exploration of user-driven innovations for every part of life is an additional area of emphasis. HPI always earns the highest positions in the CHE university ranking. Since the beginning of September the Institute has offered, an interactive Internet educational network that is open to everyone.

Hans-Joachim Allgaier | idw
Further information:

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>