Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Artificial airways good news for asthma and animals

A new ‘artificial’ airway being developed in a test tube could make it possible to develop better therapies for asthma and allergy sufferers and could reduce the need for animal testing

This development will benefit people with asthma, whose airways (breathing passages) are sensitive to pollen, dust, animal fur and viruses which cause them to be inflamed making it hard to breathe.

Academics at the University of Southampton are working with the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) on this project.

Principal Investigator on the project, Donna Davies, Professor of Respiratory, Cell and Molecular Biology in the University’s Infection, Inflammation and Repair division, is working with Professor Hywel Morgan of the University's School of Electronics and Computer Science to construct the artificial airways.

NC3R provides a UK focus for the promotion, development and implementation of the 3Rs in animal research and testing. The airways, which are being developed over a two and a half year period, will be made using tissue engineering. Layers of the cells that make up the airway tissue will be grown inside a micro-fluidic device. The cells will be grown on a tiny membrane that will allow access to both sides (the air and blood) of the cells. The device will allow researchers to fully understand how lung function is affected by air particles and allergens and to test their effects without animal testing.

'This new model will allow us to measure the transport of materials and the challenges the airways are presented with,' said Professor Hywel Morgan.

The new Mountbatten Building at the University, due for completion later this year will make it possible to develop the microfluidic devices needed to take this research forward.

Helene Murphy | alfa
Further information:

More articles from Information Technology:

nachricht Fraunhofer FIT joins Facebook's Telecom Infra Project
25.10.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT

nachricht Stanford researchers create new special-purpose computer that may someday save us billions
21.10.2016 | Stanford University

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

The gene of autumn colours

27.10.2016 | Life Sciences

Polymer scaffolds build a better pill to swallow

27.10.2016 | Life Sciences

Greater Range and Longer Lifetime

26.10.2016 | Power and Electrical Engineering

More VideoLinks >>>