Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Artificial airways good news for asthma and animals

28.04.2008
A new ‘artificial’ airway being developed in a test tube could make it possible to develop better therapies for asthma and allergy sufferers and could reduce the need for animal testing

This development will benefit people with asthma, whose airways (breathing passages) are sensitive to pollen, dust, animal fur and viruses which cause them to be inflamed making it hard to breathe.

Academics at the University of Southampton are working with the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) on this project.

Principal Investigator on the project, Donna Davies, Professor of Respiratory, Cell and Molecular Biology in the University’s Infection, Inflammation and Repair division, is working with Professor Hywel Morgan of the University's School of Electronics and Computer Science to construct the artificial airways.

NC3R provides a UK focus for the promotion, development and implementation of the 3Rs in animal research and testing. The airways, which are being developed over a two and a half year period, will be made using tissue engineering. Layers of the cells that make up the airway tissue will be grown inside a micro-fluidic device. The cells will be grown on a tiny membrane that will allow access to both sides (the air and blood) of the cells. The device will allow researchers to fully understand how lung function is affected by air particles and allergens and to test their effects without animal testing.

'This new model will allow us to measure the transport of materials and the challenges the airways are presented with,' said Professor Hywel Morgan.

The new Mountbatten Building at the University, due for completion later this year will make it possible to develop the microfluidic devices needed to take this research forward.

Helene Murphy | alfa
Further information:
http://www.soton.ac.uk
http://www.ecs.soton.ac.uk/people/hm
http://www.som.soton.ac.uk/research/iir/GROUPS/respiratory/Growth_factors/default.htm

More articles from Information Technology:

nachricht Japanese researchers develop ultrathin, highly elastic skin display
19.02.2018 | University of Tokyo

nachricht Why bees soared and slime flopped as inspirations for systems engineering
19.02.2018 | Georgia Institute of Technology

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

New tech for commercial Lithium-ion batteries finds they can be charged 5 times fast

20.02.2018 | Power and Electrical Engineering

Hidden talents: Converting heat into electricity with pencil and paper

20.02.2018 | Materials Sciences

Rare find from the deep sea

20.02.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>