This development will benefit people with asthma, whose airways (breathing passages) are sensitive to pollen, dust, animal fur and viruses which cause them to be inflamed making it hard to breathe.
Academics at the University of Southampton are working with the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) on this project.
Principal Investigator on the project, Donna Davies, Professor of Respiratory, Cell and Molecular Biology in the University’s Infection, Inflammation and Repair division, is working with Professor Hywel Morgan of the University's School of Electronics and Computer Science to construct the artificial airways.
NC3R provides a UK focus for the promotion, development and implementation of the 3Rs in animal research and testing. The airways, which are being developed over a two and a half year period, will be made using tissue engineering. Layers of the cells that make up the airway tissue will be grown inside a micro-fluidic device. The cells will be grown on a tiny membrane that will allow access to both sides (the air and blood) of the cells. The device will allow researchers to fully understand how lung function is affected by air particles and allergens and to test their effects without animal testing.
'This new model will allow us to measure the transport of materials and the challenges the airways are presented with,' said Professor Hywel Morgan.
The new Mountbatten Building at the University, due for completion later this year will make it possible to develop the microfluidic devices needed to take this research forward.
Helene Murphy | alfa
Supercomputing the emergence of material behavior
18.05.2018 | University of Texas at Austin, Texas Advanced Computing Center
Keeping a Close Eye on Ice Loss
18.05.2018 | Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar- und Meeresforschung
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
23.05.2018 | Life Sciences
23.05.2018 | Life Sciences
23.05.2018 | Physics and Astronomy