Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

UCLA Endocrinologist Awarded Prestigious NIH Grant

30.09.2009
Dr. Pinchas Cohen, professor of pediatrics at the David Geffen School of Medicine at UCLA, has won a $2 million Transformative R01 (T-R01) award from the National Institutes of Health (NIH) to fund his innovative research on mitochondrial dysfunction.

Considered the power generators of the cell, mitochondria convert oxygen and nutrients into chemical energy for the cell that fuels metabolic activities.

Mitochondrial dysfunction has been associated with many diseases, including Alzheimer's, cancer and diabetes, although its exact role in the development of these diseases remains controversial.

The new T-R01 program was specifically created under the NIH Roadmap for Medical Research to support exceptionally innovative, high risk, original or unconventional research projects that have the potential to transform a field of science. The selected projects tend to be inherently risky, but if successful, can profoundly impact a broad area of biomedical research.

Cohen’s bold proposal will test the paradigm-shifting hypothesis that previously unrecognized molecules, he dubbed “mitochondrial-derived peptides” (MDPs), play an earlier unappreciated role in the regulation of cellular and organismal function, and that disregulation of MDPs is important in disease development.

Likewise, understanding the role of MDPs may lead to development of new therapeutic and diagnostic targets. Since Alzheimer’s, cancer and diabetes particularly affect the elderly, these findings could have a significant impact as the world’s aging population continues to grow. The first of these agents, which Cohen named “small humanin-like peptides,” have already demonstrated promise in animal models of diabetes and cancer.

Cohen was one of only 42 researchers nationwide chosen for the T-R01 award. He also serves as chief of endocrinology at the Mattel Children's Hospital UCLA, as well as co-director of the UCSD/UCLA Diabetes and Endocrinology Research Center.

For more information on Cohen, research plans please visit http://nihroadmap.nih.gov/T-R01/Recipients09.asp

Amy Albin | Newswise Science News
Further information:
http://www.ucla.edu
http://nihroadmap.nih.gov/T-R01/Recipients09.asp

More articles from Awards Funding:

nachricht Extensive Funding for Research on Chromatin, Adrenal Gland, and Cancer Therapy
28.06.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Otto Hahn Medal for Jaime Agudo-Canalejo
21.06.2017 | Max-Planck-Institut für Kolloid- und Grenzflächenforschung

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

Leipzig HTP-Forum discusses "hydrothermal processes" as a key technology for a biobased economy

12.07.2017 | Event News

 
Latest News

Researchers create new technique for manipulating polarization of terahertz radiation

20.07.2017 | Information Technology

High-tech sensing illuminates concrete stress testing

20.07.2017 | Materials Sciences

First direct observation and measurement of ultra-fast moving vortices in superconductors

20.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>