Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

It does not always need to be antibiotics: healthy pig breeding

25.08.2014

Scientists found a way to reduce the application of antibiotics in pig breeding by using antimicrobial peptides. The results of the study have just been published in the scientific online-journal PLOS ONE.

Researchers investigated the application of antimicrobial peptides (AMP) as substitutes for antibiotics in liquid sperm preservation. Firstly they were able to show that AMPs fight bacteria effectively in test tubes.


Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen.

Photo: IFN Schoenow e.V.

Then they showed that two of the investigated AMPs suppressed bacterial growth in liquid preserved semen preparations if combined with a small amount of the antibiotic “gentamicin”. The sperm quality was not impeded by this addition.

Bacteria are extremely adaptable which can lead to an increasing resistance against antibiotics. This causes big problems for breeders when using artificial insemination, the method most commonly used in assisted reproductive technology in pig production worldwide.

Freshly retrieved boar ejaculates always contain bacteria. These germs are detrimental to the quality as well as the longevity of liquid preserved sperm, with dire, negative consequences for fertility. The addition of antibiotics to liquid semen is required by law and facilitates an inhibition of bacterial growth.

However, many types of bacteria quickly develop resistances to the usually applied antibiotics. Hence it is important to look for new antimicrobial alternatives.

Scientists from the German Leibniz Institute for Zoo and Wildlife Research (IZW) investigated the effect of antimicrobial peptides in cooperation with the Leibniz Institute of Molecular Pharmacology (FMP) and the Institute for Reproduction of Farm Animals Schoenow e.V. (IFN).

These molecules are naturally occurring amino acid compounds, are toxic for bacteria and can be found in nearly all organisms as a first defence against germs. For this study, synthetic cationic antimicrobial peptides were produced.

“Antimicrobial peptides do not offer a complete alternative for traditional antibiotics in liquid sperm preservation, but allow a substantial reduction in their concentration”, explains Dr Karin Müller from the IZW. “This is a benefit for people as well, as the occurrence of resistance will be reduced if fewer antibiotics are used.”

Additional application possibilities are conceivable, outlines Dr Margitta Dathe from the FMP. “Antimicrobial peptides could be used for the preservation of other cells as well. Furthermore special AMPs for the treatment of superficial infections could be developed.”

Publication:
Speck S, Courtiol A, Junkes C, Dathe M, Mueller K, Schulze M (2014): Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen. PLOS ONE

Previous publication:
Schulze M, Junkes C, Mueller P, Speck S, Ruediger K, Dathe M, Mueller K (2014): Effects of cationic antimicrobial peptides on liquid-preserved boar spermatozoa. PLOS ONE 9(6): e100490. doi: 10.1371/journal.pone.0100490

Contact:
Dr. Karin Müller
Tel.: +49 30 5168-125
mueller@izw-berlin.de

Dr. Margitta Dathe
Tel.: +49 30 947 93 274
dathe@fmp-berlin.de

Steven Seet
(Press Officer)
Tel.: +49 30 5168-125
seet@izw-berlin.de

Background information:
The Leibniz Institute for Zoo and Wildlife Research (IZW) investigates the vitality and adaptability of wildlife populations in mammalian and avian species of outstanding ecological interest that face anthropogenic challenges. It studies the adaptive value of traits in the life cycle of wildlife, wildlife diseases and clarifies the biological basis and development of methods for the protection of threatened species. Such knowledge is a precondition for a scientifically based approach to conservation and for the development of concepts for the ecologically sustainable use of natural resources. The IZW belongs to the Forschungsverbund Berlin e.V. (www.fv-berlin.de)
www.izw-berlin.de

Weitere Informationen:

http://www.izw-berlin.de
http://www.fmp-berlin.de
http://www.ifn-schoenow.de

Karl-Heinz Karisch | Forschungsverbund Berlin e.V.

Further reports about: AMPs Forschungsverbund IZW Reproduction Wildlife antimicrobial healthy

More articles from Agricultural and Forestry Science:

nachricht Plasma-zapping process could yield trans fat-free soybean oil product
02.12.2016 | Purdue University

nachricht New findings about the deformed wing virus, a major factor in honey bee colony mortality
11.11.2016 | Veterinärmedizinische Universität Wien

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>