Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

It does not always need to be antibiotics: healthy pig breeding

25.08.2014

Scientists found a way to reduce the application of antibiotics in pig breeding by using antimicrobial peptides. The results of the study have just been published in the scientific online-journal PLOS ONE.

Researchers investigated the application of antimicrobial peptides (AMP) as substitutes for antibiotics in liquid sperm preservation. Firstly they were able to show that AMPs fight bacteria effectively in test tubes.


Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen.

Photo: IFN Schoenow e.V.

Then they showed that two of the investigated AMPs suppressed bacterial growth in liquid preserved semen preparations if combined with a small amount of the antibiotic “gentamicin”. The sperm quality was not impeded by this addition.

Bacteria are extremely adaptable which can lead to an increasing resistance against antibiotics. This causes big problems for breeders when using artificial insemination, the method most commonly used in assisted reproductive technology in pig production worldwide.

Freshly retrieved boar ejaculates always contain bacteria. These germs are detrimental to the quality as well as the longevity of liquid preserved sperm, with dire, negative consequences for fertility. The addition of antibiotics to liquid semen is required by law and facilitates an inhibition of bacterial growth.

However, many types of bacteria quickly develop resistances to the usually applied antibiotics. Hence it is important to look for new antimicrobial alternatives.

Scientists from the German Leibniz Institute for Zoo and Wildlife Research (IZW) investigated the effect of antimicrobial peptides in cooperation with the Leibniz Institute of Molecular Pharmacology (FMP) and the Institute for Reproduction of Farm Animals Schoenow e.V. (IFN).

These molecules are naturally occurring amino acid compounds, are toxic for bacteria and can be found in nearly all organisms as a first defence against germs. For this study, synthetic cationic antimicrobial peptides were produced.

“Antimicrobial peptides do not offer a complete alternative for traditional antibiotics in liquid sperm preservation, but allow a substantial reduction in their concentration”, explains Dr Karin Müller from the IZW. “This is a benefit for people as well, as the occurrence of resistance will be reduced if fewer antibiotics are used.”

Additional application possibilities are conceivable, outlines Dr Margitta Dathe from the FMP. “Antimicrobial peptides could be used for the preservation of other cells as well. Furthermore special AMPs for the treatment of superficial infections could be developed.”

Publication:
Speck S, Courtiol A, Junkes C, Dathe M, Mueller K, Schulze M (2014): Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen. PLOS ONE

Previous publication:
Schulze M, Junkes C, Mueller P, Speck S, Ruediger K, Dathe M, Mueller K (2014): Effects of cationic antimicrobial peptides on liquid-preserved boar spermatozoa. PLOS ONE 9(6): e100490. doi: 10.1371/journal.pone.0100490

Contact:
Dr. Karin Müller
Tel.: +49 30 5168-125
mueller@izw-berlin.de

Dr. Margitta Dathe
Tel.: +49 30 947 93 274
dathe@fmp-berlin.de

Steven Seet
(Press Officer)
Tel.: +49 30 5168-125
seet@izw-berlin.de

Background information:
The Leibniz Institute for Zoo and Wildlife Research (IZW) investigates the vitality and adaptability of wildlife populations in mammalian and avian species of outstanding ecological interest that face anthropogenic challenges. It studies the adaptive value of traits in the life cycle of wildlife, wildlife diseases and clarifies the biological basis and development of methods for the protection of threatened species. Such knowledge is a precondition for a scientifically based approach to conservation and for the development of concepts for the ecologically sustainable use of natural resources. The IZW belongs to the Forschungsverbund Berlin e.V. (www.fv-berlin.de)
www.izw-berlin.de

Weitere Informationen:

http://www.izw-berlin.de
http://www.fmp-berlin.de
http://www.ifn-schoenow.de

Karl-Heinz Karisch | Forschungsverbund Berlin e.V.

Further reports about: AMPs Forschungsverbund IZW Reproduction Wildlife antimicrobial healthy

More articles from Agricultural and Forestry Science:

nachricht Alkaline soil, sensible sensor
03.08.2017 | American Society of Agronomy

nachricht New 3-D model predicts best planting practices for farmers
26.06.2017 | Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>