Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

It does not always need to be antibiotics: healthy pig breeding

25.08.2014

Scientists found a way to reduce the application of antibiotics in pig breeding by using antimicrobial peptides. The results of the study have just been published in the scientific online-journal PLOS ONE.

Researchers investigated the application of antimicrobial peptides (AMP) as substitutes for antibiotics in liquid sperm preservation. Firstly they were able to show that AMPs fight bacteria effectively in test tubes.


Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen.

Photo: IFN Schoenow e.V.

Then they showed that two of the investigated AMPs suppressed bacterial growth in liquid preserved semen preparations if combined with a small amount of the antibiotic “gentamicin”. The sperm quality was not impeded by this addition.

Bacteria are extremely adaptable which can lead to an increasing resistance against antibiotics. This causes big problems for breeders when using artificial insemination, the method most commonly used in assisted reproductive technology in pig production worldwide.

Freshly retrieved boar ejaculates always contain bacteria. These germs are detrimental to the quality as well as the longevity of liquid preserved sperm, with dire, negative consequences for fertility. The addition of antibiotics to liquid semen is required by law and facilitates an inhibition of bacterial growth.

However, many types of bacteria quickly develop resistances to the usually applied antibiotics. Hence it is important to look for new antimicrobial alternatives.

Scientists from the German Leibniz Institute for Zoo and Wildlife Research (IZW) investigated the effect of antimicrobial peptides in cooperation with the Leibniz Institute of Molecular Pharmacology (FMP) and the Institute for Reproduction of Farm Animals Schoenow e.V. (IFN).

These molecules are naturally occurring amino acid compounds, are toxic for bacteria and can be found in nearly all organisms as a first defence against germs. For this study, synthetic cationic antimicrobial peptides were produced.

“Antimicrobial peptides do not offer a complete alternative for traditional antibiotics in liquid sperm preservation, but allow a substantial reduction in their concentration”, explains Dr Karin Müller from the IZW. “This is a benefit for people as well, as the occurrence of resistance will be reduced if fewer antibiotics are used.”

Additional application possibilities are conceivable, outlines Dr Margitta Dathe from the FMP. “Antimicrobial peptides could be used for the preservation of other cells as well. Furthermore special AMPs for the treatment of superficial infections could be developed.”

Publication:
Speck S, Courtiol A, Junkes C, Dathe M, Mueller K, Schulze M (2014): Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen. PLOS ONE

Previous publication:
Schulze M, Junkes C, Mueller P, Speck S, Ruediger K, Dathe M, Mueller K (2014): Effects of cationic antimicrobial peptides on liquid-preserved boar spermatozoa. PLOS ONE 9(6): e100490. doi: 10.1371/journal.pone.0100490

Contact:
Dr. Karin Müller
Tel.: +49 30 5168-125
mueller@izw-berlin.de

Dr. Margitta Dathe
Tel.: +49 30 947 93 274
dathe@fmp-berlin.de

Steven Seet
(Press Officer)
Tel.: +49 30 5168-125
seet@izw-berlin.de

Background information:
The Leibniz Institute for Zoo and Wildlife Research (IZW) investigates the vitality and adaptability of wildlife populations in mammalian and avian species of outstanding ecological interest that face anthropogenic challenges. It studies the adaptive value of traits in the life cycle of wildlife, wildlife diseases and clarifies the biological basis and development of methods for the protection of threatened species. Such knowledge is a precondition for a scientifically based approach to conservation and for the development of concepts for the ecologically sustainable use of natural resources. The IZW belongs to the Forschungsverbund Berlin e.V. (www.fv-berlin.de)
www.izw-berlin.de

Weitere Informationen:

http://www.izw-berlin.de
http://www.fmp-berlin.de
http://www.ifn-schoenow.de

Karl-Heinz Karisch | Forschungsverbund Berlin e.V.

Further reports about: AMPs Forschungsverbund IZW Reproduction Wildlife antimicrobial healthy

More articles from Agricultural and Forestry Science:

nachricht How algae could save plants from themselves
11.05.2016 | Carnegie Institution for Science

nachricht Biofeedback system designed to control photosynthetic lighting
10.05.2016 | American Society for Horticultural Science

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Worldwide Success of Tyrolean Wastewater Treatment Technology

A biological and energy-efficient process, developed and patented by the University of Innsbruck, converts nitrogen compounds in wastewater treatment facilities into harmless atmospheric nitrogen gas. This innovative technology is now being refined and marketed jointly with the United States’ DC Water and Sewer Authority (DC Water). The largest DEMON®-system in a wastewater treatment plant is currently being built in Washington, DC.

The DEMON®-system was developed and patented by the University of Innsbruck 11 years ago. Today this successful technology has been implemented in about 70...

Im Focus: Computational high-throughput screening finds hard magnets containing less rare earth elements

Permanent magnets are very important for technologies of the future like electromobility and renewable energy, and rare earth elements (REE) are necessary for their manufacture. The Fraunhofer Institute for Mechanics of Materials IWM in Freiburg, Germany, has now succeeded in identifying promising approaches and materials for new permanent magnets through use of an in-house simulation process based on high-throughput screening (HTS). The team was able to improve magnetic properties this way and at the same time replaced REE with elements that are less expensive and readily available. The results were published in the online technical journal “Scientific Reports”.

The starting point for IWM researchers Wolfgang Körner, Georg Krugel, and Christian Elsässer was a neodymium-iron-nitrogen compound based on a type of...

Im Focus: Atomic precision: technologies for the next-but-one generation of microchips

In the Beyond EUV project, the Fraunhofer Institutes for Laser Technology ILT in Aachen and for Applied Optics and Precision Engineering IOF in Jena are developing key technologies for the manufacture of a new generation of microchips using EUV radiation at a wavelength of 6.7 nm. The resulting structures are barely thicker than single atoms, and they make it possible to produce extremely integrated circuits for such items as wearables or mind-controlled prosthetic limbs.

In 1965 Gordon Moore formulated the law that came to be named after him, which states that the complexity of integrated circuits doubles every one to two...

Im Focus: Researchers demonstrate size quantization of Dirac fermions in graphene

Characterization of high-quality material reveals important details relevant to next generation nanoelectronic devices

Quantum mechanics is the field of physics governing the behavior of things on atomic scales, where things work very differently from our everyday world.

Im Focus: Graphene: A quantum of current

When current comes in discrete packages: Viennese scientists unravel the quantum properties of the carbon material graphene

In 2010 the Nobel Prize in physics was awarded for the discovery of the exceptional material graphene, which consists of a single layer of carbon atoms...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Networking 4.0: International Laser Technology Congress AKL’16 Shows New Ways of Cooperations

24.05.2016 | Event News

Challenges of rural labor markets

20.05.2016 | Event News

International expert meeting “Health Business Connect” in France

19.05.2016 | Event News

 
Latest News

11 million Euros for research into magnetic field sensors for medical diagnostics

27.05.2016 | Awards Funding

Fungi – a promising source of chemical diversity

27.05.2016 | Life Sciences

New Model of T Cell Activation

27.05.2016 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>