Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

AgriLife scientist: Functional amino acids regulate key metabolic pathways

22.11.2010
Functional amino acids play a critical role in the development of both animals and humans, according to a Texas AgriLife Research scientist.

In a journal article appearing in the American Society for Nutrition (Advances in Nutrition 1:31-37, 2010), Dr. Guoyao Wu, AgriLife Research animal nutritionist and senior faculty fellow in the department of animal science at Texas A&M University, calls for scientists to "think out of the box” and place more emphasis on this area of study.

"We need to move forward and capitalize on the potential of functional amino acids in improving health and animal production," he said.

A functional amino acid is an amino acid that can regulate key metabolic pathways to improve health, growth, development and reproduction of animals and humans, Wu said.

"This involves cell signaling through amino acids and their metabolites, and the metabolic pathways may include protein synthesis, antioxidative reactions and oxidation of energy substrates," he said. "A functional amino acid can be either a 'nonessential' or an 'essential' amino acid."

Past research emphasis has focused primarily on essential amino acids. However, Wu says both essential amino acids and non-essential amino acids should be taken into consideration.

"This is important when formulating balanced diets to maximize growth performance in livestock species, poultry and fish," he said. "It is also recommended that nonessential amino acids be provided to humans to prevent growth retardation and chronic diseases."

Wu's previous research discovered that arginine, an amino acid, contributes many positive benefits in growth and embryo development in pigs, sheep and rats. Arginine also aids in fighting obesity. Wu has identified this as an important area for expanded research on new amino acids and health.

"Currently in the U.S., more than 60 percent of adults are overweight or obese," he said. "Globally, more than 300 million adults are obese and more than 1 billion are overweight. Also, a large number of children in the U.S. and other countries are overweight or obese. The most urgent needs of new research in amino acids and health are the roles of functional amino acids in the treatment and prevention of obesity and its associated cardiovascular dysfunction."

Wu also said that dietary supplementation with arginine can help improve meat quality in pigs prior to slaughter.

The two top scientific discoveries in the field of amino acids and health over the past two decades are nitric oxide synthesis from arginine and the role of amino acids in cell signaling.

"An important area of research in the next few years may be to study the molecular and cellular mechanisms whereby some amino acids (e.g., arginine) can regulate metabolic pathways in animals and humans," he said. "An example is how arginine reduces obesity and ameliorates the metabolic syndrome, and how elevated levels of leucine may contribute to mitochondrial dysfunction and insulin resistance (including vascular resistance) in obese subjects."

He said "unquestionably" recent advances in understanding functional amino acids are "expanding our basic knowledge of protein metabolism and transforming practices of nutrition worldwide."

Though nutritional studies conducted on animals have benefited human health, Wu suggests that caution should be taken to "extrapolate animal data to humans" as dietary requirements differ from one species to another.

Wu said that humans need diets with balanced portions of amino acids for cardiovascular and reproductive health.

Dr. Guoyao Wu | EurekAlert!
Further information:
http://www.tamu.edu

More articles from Agricultural and Forestry Science:

nachricht Alkaline soil, sensible sensor
03.08.2017 | American Society of Agronomy

nachricht New 3-D model predicts best planting practices for farmers
26.06.2017 | Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Nagoya physicists resolve long-standing mystery of structure-less transition

21.08.2017 | Materials Sciences

Chronic stress induces fatal organ dysfunctions via a new neural circuit

21.08.2017 | Health and Medicine

Scientists from the MSU studied new liquid-crystalline photochrom

21.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>