Rewiring the egg: mechanism remains murky.

From a scientific viewpoint, the cloning of human embryos may be more of a step than a leap, say sceptics. If the signals that turn adult cells into embryonic ones can be found, the creation of cloned embryos for tissue repair may become redundant.

Researchers at Advanced Cell Technology (ACT) in Worcester, Massachusetts, now report that they have created cloned human embryos. They aimed to make blastocysts, hollow balls of cells fr

The size and types of the largest local land animals vary greatly from place to place, prompting scientists to question what controls the success of animals of certain sizes over others. Now a report published in the current issue of the Proceedings of the National Academy of Sciences shows that the size of a landmass limits the maximal body size of its top animal.

Gary Burness and Jared Diamond of the University of California School of Medicine, together with Timothy Flannery of the South

New research is helping to unravel the machinery that allows a mosquito to sniff out its human quarry, which could lead to more and better ways of foiling the disease-spreading insects. A report published today in the online version of the Proceedings of the National Academy of Sciences describes four genes that appear to produce odor-sensing molecules in Africa’s Anopheles gambiae, a carrier of malaria, the number two killer in the developing world. Understanding how such genes operate could en

An immune system chemical may undo skin damage by sunlight.

A chemical involved in immune-system signalling may be able to reverse some types of skin damage caused by sunlight. It could reduce sunburn by activating DNA-repair mechanisms, a new study suggests, raising the possibility that the chemical might be used to prevent or treat skin cancer 1 .

High-energy ultraviolet light is thought to promote skin cancer by damaging the DNA within cells. Skin cancer,

Programmed molecules build themselves into a bone-mimic.

Scientists in the United States have made self-assembling synthetic bone 1 . Carefully designed building-blocks join up to mimic bone’s complex molecular-scale architecture, bringing better prosthetics a step closer.

Materials engineers are keen to emulate the strength and toughness of biominerals such as bone, tooth and shell. Mollusc shells, for example, a composite of the mineral calcium carbonate a

While prion diseases seem to be waning in humans, they could be waxing in sheep.

Variant Creutzfeldt-Jakob disease (vCJD) may claim only around 200 victims, a new model predicts 1 . This degenerative brain disease is thought to occur when people are exposed to misfolded prion proteins from meat infected with bovine spongiform encephalopathy (BSE or ’mad cow disease’).

Meanwhile, another study warns that a huge BSE epidemic could be brewing in the UK