Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

White Matter Changes May Predict Dementia Risk

14.07.2009
Elderly people with no memory or thinking problems are more likely to later develop thinking problems if they have a growing amount of “brain rust,” or small areas of brain damage, according to a study published in the July 14, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

For the study, researchers followed 49 people age 65 and older who had no memory or thinking problems for an average of 9.5 years. The participants had at least three brain scans and annual tests of thinking skills. During the study, 24 of the participants developed persistent cognitive impairment, or memory problems that are a potential precursor to Alzheimer’s disease or another type of dementia.

The study found that those who had the fastest rate of growth in the amount of small areas of brain damage, or white matter hyperintensities, were more likely to later develop permanent thinking problems that in many cases led to dementia than those with a slow rate of growth in these types of brain lesions. Every cubic centimeter (less than a quarter of a teaspoon) increase in the amount of brain lesions was associated with a 94 percent increased risk of developing cognitive impairment.

The total amount of brain lesions at the beginning of the study was not a predictor of risk of developing cognitive impairment after taking into consideration the rate of change of these brain lesions over time.

“We need to determine factors that can decrease the accumulation of white matter hyperintensities over time,” said study author Lisa Silbert, MD, MCR, of Oregon Health & Science University in Portland and a member of the American Academy of Neurology. “We also need to determine how to identify those who are vulnerable to this accumulation so they can be targeted for potential early prevention or treatment methods.”

The study was supported by the Department of Veterans Affairs, National Institutes of Health, Paul B. Beeson Career Development Award in Aging, Max Millis Fund for Neurological Research, and Storms Family Fund at the Oregon Community Foundation.

The American Academy of Neurology, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer’s disease, epilepsy, Parkinson’s disease, and multiple sclerosis.

Rachel L. Seroka | American Academy of Neurology
Further information:
http://www.aan.com
http://www.TheBrainMatters.org

More articles from Health and Medicine:

nachricht Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Foods of the future
15.08.2018 | Georg-August-Universität Göttingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: It’s All in the Mix: Jülich Researchers are Developing Fast-Charging Solid-State Batteries

There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.

The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Air pollution leads to cardiovascular diseases

21.08.2018 | Ecology, The Environment and Conservation

Researchers target protein that protects bacteria's DNA 'recipes'

21.08.2018 | Life Sciences

A paper battery powered by bacteria

21.08.2018 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>