Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sonography complements physical exam in identifying juvenile inflammatory arthritis in children

05.05.2011
Juvenile Inflammatory Arthritis (JIA) is a potentially debilitating childhood disease.

Early detection and treatment of active arthritis may avert long term joint damage and disability. Research has shown that sonography with power Doppler can facilitate making assessments in joint activity and sub-clinical disease, according to research being presented at the 2011 American Roentgen Ray Society's annual meeting.

The study, performed at Albert Einstein College of Medicine's Montefiore Medical Center, in Bronx, NY, compares sonography with power Doppler to physical examination in evaluating disease activity in the knees and ankles of children with JIA.

Eighty-four joints in 19 patients were evaluated; of these, 65 joints were concordant on both sonography and physical examination. Of the remaining 19 joints, 14 were active on sonography and inactive on physical examination. Five of the 14 joints were found to have subclinical disease at the time of the initial physical examination, while 8 of the 14 joints demonstrated mild hyperemia as the only indicator of disease activity on sonography, which was a false positive. Of the 5 joints active on physical examination and inactive on sonography, 4 had subtalar disease.

"In patients with at least one active joint on physical examination, ultrasound augments the physical exam by identifying subclinical disease (in other joints). Our study confirmed that patients with evidence of subclinical disease do, in many cases, go on to have clinically evident disease," said Vikash Panghaal, MD, lead author of the study.

"Certain combinations of physical exam findings are highly sensitive, and in these instances, ultrasound does not contribute to clinical management. Subtalar disease is poorly assessed using ultrasound," he said.

"Unlike previous studies, our study included a 2-5 month follow-up physical exam after the initial physical exam and ultrasound, which allowed confirmation of subclinical disease," said Dr. Panghaal. "We also determined the sensitivity and specificity of various aspects of the physical exam for identifying synovitis and correlated this with ultrasound findings," said Dr. Panghaal.

This abstract is being presented in conjunction with the 2011 American Roentgen Ray Society's annual meeting. For a copy of the full study or to request an interview with the lead author, please contact Keri Sperry via email at ksperry@arrs.org or 703-296-3104.

Keri Sperry | EurekAlert!
Further information:
http://www.arrs.org

More articles from Health and Medicine:

nachricht Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Foods of the future
15.08.2018 | Georg-August-Universität Göttingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: It’s All in the Mix: Jülich Researchers are Developing Fast-Charging Solid-State Batteries

There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.

The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Quantum bugs, meet your new swatter

20.08.2018 | Information Technology

A novel synthetic antibody enables conditional “protein knockdown” in vertebrates

20.08.2018 | Life Sciences

Metamolds: Molding a mold

20.08.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>