The research on this hereditary disease has been developed in the Area of Genetic Therapy and Hepatology of the CIMA. Dr. Jesús Prieto coordinated the research, which was carried out by scientists Gloria González Aseguinolaza, Astrid Pañeda, Rubén Hernández Alcoceba and Antonio Fontanellas. The symptoms of this disease appear when there are anomalies in the production of heme, a basic substance for the synthesis of vital proteins such as hemoglobin, myoglobin and cytochrome.
Among the problems that this disease causes, which until now have been incurable, are included internal neuropsychological disturbances and severe stomach pains. As well, acute attacks of porphyria can be fatal if they cause grave neurological complications.
Persons affected will intermittently suffer from the symptoms of porphyria throughout their entire life. Upon occasion, they appear in adolescence and more frequently in adulthood, with greater occurrence in women. Some medicines, such as barbiturates, tranquilizers and sedatives, can trigger the disease; as well as diets, hormonal irregularities, tobacco, alcohol, infections or emotional and physical stress.
After testing the effectiveness of the treatment, the CIMA and the AMT have obtained exclusive rights to synthesize and develop the medications. Currently, the clinical phase is scheduled to begin in 2008 and the treatments should be available to the public in 2010.
Egoitz Etxebeste | basqueresearch
Collagen nanofibrils in mammalian tissues get stronger with exercise
14.12.2018 | University of Illinois College of Engineering
New discoveries predict ability to forecast dementia from single molecule
12.12.2018 | UT Southwestern Medical Center
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
14.12.2018 | Power and Electrical Engineering
14.12.2018 | Physics and Astronomy
14.12.2018 | Physics and Astronomy