Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nutritional supplement reduces need for traditional ulcerative colitis treatment

07.04.2005


According to a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, a nutritionally complete oral supplement enriched with fish oil, soluble fiber and antioxidants reduces reliance on traditional therapies for people with ulcerative colitis. Moreover, people who took the oral supplement were less likely to start corticosteroid drug therapy, which has many long-term side effects.



"Our study proves that an oral supplement which combines fish oil, soluble fiber and antioxidants is safer and causes fewer side effects than many of the medications currently available to treat ulcerative colitis," said Douglas Seidner, MD, lead study author with The Cleveland Clinic. "This supplement will provide yet another treatment option to alleviate symptoms for patients suffering from this debilitating disease."

Researchers at The Cleveland Clinic conducted a randomized controlled clinical trial of patients 18 and older with mild to moderate active ulcerative colitis to assess the benefits of adding this oral supplement to standard medical therapy for the disease. This study shows that patients on corticosteroid therapy who were given the oral supplement vs. a placebo had a significant reduction in the dose of corticosteroids needed to control clinical symptoms of ulcerative colitis.


Ulcerative colitis is an inflammatory bowel disease in which the lining of the large intestine becomes inflamed and ulcerated, and most commonly affects people between 15 and 40 years of age. Ulcerative colitis can be attributed to an immune disorder or heredity, among other things, and is characterized by abdominal cramps, bloody diarrhea and fever.

Treatments for the disease, including corticosteroids and mesalamine are intended to control inflammation. While corticosteroids are highly effective in the treatment of ulcerative colitis, prolonged use often leads to insomnia, mood alterations, increased appetite, hypertension, osteoporosis and other adverse events.

Adverse effects of corticosteroid use are a concern to physicians and lead to discontinuation of the therapy by many patients. However, more than 25 percent of patients who discontinue the therapy have a relapse of symptoms. Previous smaller studies have shown that fish oil is effective in reducing the need for corticosteroids in ulcerative colitis patients. The current study combines fish oil with soluble fiber to diminish the inflammation associated with ulcerative colitis symptoms and positively affect nutrition.

"The need to find new treatments that are safe, effective and inexpensive remains and physicians should consider adding this combination of active ingredients as an adjuvant therapy for ulcerative colitis," said Seidner.

Kimberly Wise | EurekAlert!
Further information:
http://www.gastro.org
http://www.cghjournal.org

More articles from Health and Medicine:

nachricht Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University

nachricht Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>