Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Effect of Soy Protein with Isoflavones on Postmenopausal Women

08.07.2004


No beneficial effects were found on cognitive function, bone mineral density or plasma lipids when postmenopausal women age 60 years or older took soy protein supplements with isoflavones for one year, according to a study in the July 7 issue of The Journal of the American Medical Association (JAMA).



“The sudden decline in estrogen levels after menopause coincides with acceleration of several aging processes,” according to background information in the article. “On average, bone mineral density (BMD) decreases and cognitive function declines, whereas total cholesterol and low-density lipoprotein cholesterol (LDL-C) [the bad type of cholesterol] increase.” The authors write that some women have taken hormone therapy to counteract some of these changes; however, hormone therapy has short- and long-term risks. Isoflavones, estrogenlike compounds naturally occurring in plant foods, have been suggested as an alternative for traditional estrogen therapy with fewer adverse effects.

Sanne Kreijkamp-Kaspers, M.D., Ph.D., from the University Medical Center, Utrecht, the Netherlands, and colleagues conducted a study with 202 healthy postmenopausal women aged 60 to 75 years between April 2000 and September 2001 in the Netherlands. The women were randomly assigned to receive 25.6 grams of soy protein containing 99 milligrams (mg) of isoflavones or the placebo, a total milk protein as a powder, each of which could be mixed with food or beverages on a daily basis for 12 months. Cognitive testing was performed at baseline and at the final visit, one year later, using several standardized tests. Bone mineral density was measured at baseline and 12 months using dual-energy x-ray absorptiometry (DXA) scans, and plasma lipid levels also were assessed at baseline and 12 months.


“In this longer-term, relatively large double-blind, placebo-controlled , randomized trial, we did not find any effect of soy protein supplementation, which naturally contains large amounts of isoflavones, on cognitive function, BMD, or plasma lipids in the relevant population of aging women,” the authors report. Timing of the supplementation may provide an explanation for the difference in findings from this study compared to previous ones that were more promising, the authors write. “…the most pronounced effects of estrogen on cognitive function have been reported in perimenopausal women, and not in late postmenopausal women. With respect to bone, it has been suggested that it is easier to prevent changes or losses after menopause than reverse them when they have already taken place. … The influence of the timing of supplementation needs to be elucidated in further research,” the authors suggest.

| newswise
Further information:
http://www.jama.com

More articles from Health and Medicine:

nachricht Neutrons produce first direct 3D maps of water during cell membrane fusion
21.09.2018 | DOE/Oak Ridge National Laboratory

nachricht Narcolepsy, scientists unmask the culprit of an enigmatic disease
20.09.2018 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists present new observations to understand the phase transition in quantum chromodynamics

The building blocks of matter in our universe were formed in the first 10 microseconds of its existence, according to the currently accepted scientific picture. After the Big Bang about 13.7 billion years ago, matter consisted mainly of quarks and gluons, two types of elementary particles whose interactions are governed by quantum chromodynamics (QCD), the theory of strong interaction. In the early universe, these particles moved (nearly) freely in a quark-gluon plasma.

This is a joint press release of University Muenster and Heidelberg as well as the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.

Then, in a phase transition, they combined and formed hadrons, among them the building blocks of atomic nuclei, protons and neutrons. In the current issue of...

Im Focus: Patented nanostructure for solar cells: Rough optics, smooth surface

Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.

"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...

Im Focus: New soft coral species discovered in Panama

A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.

Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...

Im Focus: New devices based on rust could reduce excess heat in computers

Physicists explore long-distance information transmission in antiferromagnetic iron oxide

Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.

Im Focus: Finding Nemo's genes

An international team of researchers has mapped Nemo's genome

An international team of researchers has mapped Nemo's genome, providing the research community with an invaluable resource to decode the response of fish to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

"Boston calling": TU Berlin and the Weizenbaum Institute organize a conference in USA

21.09.2018 | Event News

One of the world’s most prominent strategic forums for global health held in Berlin in October 2018

03.09.2018 | Event News

4th Intelligent Materials - European Symposium on Intelligent Materials

27.08.2018 | Event News

 
Latest News

Astrophysicists measure precise rotation pattern of sun-like stars for the first time

21.09.2018 | Physics and Astronomy

Brought to light – chromobodies reveal changes in endogenous protein concentration in living cells

21.09.2018 | Life Sciences

"Boston calling": TU Berlin and the Weizenbaum Institute organize a conference in USA

21.09.2018 | Event News

VideoLinks
Science & Research
Overview of more VideoLinks >>>