Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Promoting the brain image bank

12.05.2004


Researchers promote collecting and sharing data from brain studies with their fMRI Data Center. Clockwise from upper left: Scott Grafton, Daniel Rockmore, Michael Gazzaniga and John Van Horn. (photo by Joe Mehling ’69)


The dream of saving and sharing functional magnetic resonance imaging (fMRI) data is quickly becoming a reality, according to Dartmouth researchers who run the fMRI Data Center, which archives and distributes the raw data from studies that track brain activity using fMRI. The Dartmouth researchers wrote an essay in the May issue of Nature Neuroscience about the initial reluctance and gradual acceptance of the center, and they describe the many attributes a center such as theirs offers the scientific community.

"The fMRI Data Center was created with sharing information in mind," says John Van Horn, the lead author on the paper and a Research Associate Professor of Psychological and Brain Sciences. "We wanted to advance and expand the cognitive neuroscience field by making the raw data accessible to more people for free."

According to the essay, the faculty who created the fMRI Data Center in 2000 were met with initial resistance from fellow neuroscientists. Some researchers were hesitant to give away their data; some questioned whether new science could arise from old data; and others thought that the technical hurdles could not be overcome. Despite these concerns, the Dartmouth group went ahead and teamed up with the Journal of Cognitive Neuroscience and made it a requirement to include raw fMRI data when submitting research to the publication. With initial support from the National Science Foundation, the W.M. Keck Foundation and the National Institute of Mental Health, the computer equipment was purchased and fMRI Data Center was established.



Now, four years later, the fMRI Data Center has archived more than 70 complete fMRI studies, which includes data from about 1,000 individuals. They have fulfilled, at no charge, more than 1,200 requests for data from researchers around the world. The overall size of their collection is about 2.6 terabytes (for comparison, about ten terabytes could hold the entire printed collection of the Library of Congress).

"We persevered in spite of the reception we received at first," says Van Horn, who serves as Operations Director for the fMRI Data Center. "We have created a repository of valuable information that continues to grow, and adding to it has become a natural part of the academic publishing process."

Van Horn wrote the piece with colleagues who were all instrumental in creating the fMRI Data Center: Scott Grafton, Professor of Psychological and Brain Sciences and the Director of the Dartmouth Brain Imaging Center; Daniel Rockmore, Professor of Mathematics and Computer Science; and Michael Gazzaniga, Professor of Psychological and Brain Sciences, Director of the Center for Cognitive Neuroscience and Dean of the Faculty. The authors note that early fears about fMRI sharing dat a have been overcome, and reusing data has proven fruitful to reanalyze previous findings or pursue related research questions that weren’t considered originally. Using archived data for new studies provides new perspectives on data, the authors say, which contributes to the effort to better understand the fundamentals of human cognition.

The Nature Neuroscience essay is part of a special issue dedicated to research efforts that use enormous amounts of data and computational power, such as fMRI studies, proteomics and genomics endeavors that involve protein and gene analysis.

Sue Knapp | Dartmouth College
Further information:
http://www.dartmouth.edu/~news/releases/2004/05/11.html

More articles from Health and Medicine:

nachricht New antibody analysis accelerates rational vaccine design
09.08.2018 | Scripps Research Institute

nachricht Distrust of power influences choice of medical procedures
01.08.2018 | Johannes Gutenberg-Universität Mainz

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

Im Focus: World record: Fastest 3-D tomographic images at BESSY II

The quality of materials often depends on the manufacturing process. In casting and welding, for example, the rate at which melts solidify and the resulting microstructure of the alloy is important. With metallic foams as well, it depends on exactly how the foaming process takes place. To understand these processes fully requires fast sensing capability. The fastest 3D tomographic images to date have now been achieved at the BESSY II X-ray source operated by the Helmholtz-Zentrum Berlin.

Dr. Francisco Garcia-Moreno and his team have designed a turntable that rotates ultra-stably about its axis at a constant rotational speed. This really depends...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

'Building up' stretchable electronics to be as multipurpose as your smartphone

14.08.2018 | Information Technology

During HIV infection, antibody can block B cells from fighting pathogens

14.08.2018 | Life Sciences

First study on physical properties of giant cancer cells may inform new treatments

14.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>