Recoverying from third and fourth degree burns, the most damaging types, is a slow and painful process that inevitably leaves excessive scar tissue. Russian researchers have developed a pharmacological enzyme preparation to accelerate the debridement process and wound healing, which reduces the preparation time for grafting and diminishes scarring.
Their product, called ENZYCOL, is a mixture of collagenases from the Kamchatka crab that rapidly dissolves the dense collagen matrix of necrotic skin forming after a burn. By removing this non-living tissue, ENZYCOL promotes the healing of the surrounding healthy tissue, a vital process for preventing the onset of infection. The debridement period for burns pre-treated with the crab collagenase mixture is 2 days shorter than with traditional enzyme therapies such as trypsin.
The research team consisted of scientists from the Russian Cardiology Research Center in Moscow and the Research Center of Toxicology and Hygienic Regulation of Biopreparations in Serpukhov (Moscow Region). Seventy-one scientists and technical staff, of which forty represented former biological and chemical weapons experts, participated in two ISTC projects to develop this technology. They began their work in 1999 to develop the powder preparation and confirm its safety and effectiveness in vitro. In the follow-up project, which began in 2002 and is currently going on, the scientists modified the method for preparing ENZYCOL to make it suitable for pilot scale production. They also performed pre-clinical trials on laboratory animals, which proved that the enzyme cocktail is non-toxic, non-mutagenic, and non-irritating on skin.
Alexander Ivanchenko | alfa
The genes are not to blame
20.07.2018 | Technische Universität München
Targeting headaches and tumors with nano-submarines
20.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences