New research led by a University of North Carolina at Chapel Hill scientist shows for the first time how Mycobacterium tuberculosis, the germ responsible for TB, uses a system for releasing proteins to help it survive the lungs immune defenses to spread and cause disease.
The study, published online in the April issue of Molecular Microbiology, also adds crucial new knowledge to the molecular factors that underlie the virulence of M. tuberculosis and may aid development of new, targeted treatments for the disease.
"I think this study moves us along in our understanding of TB pathogenesis," said study lead author Dr. Miriam Braunstein, assistant professor of microbiology and immunology at UNCs School of Medicine.
Leslie Lang | EurekAlert!
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