Study findings have implications for patients' access to new treatments
A proportion of idiopathic pulmonary fibrosis (IPF) cases may be linked with asbestos exposure, according to the results of a new study. If confirmed, the findings would mean that current treatment strategies need to be altered as people with a history of asbestos exposure are not currently able to access new treatments for IPF.
The research, which was presented at the European Respiratory Society's International Congress today (09 September 2014), provided new mortality data for IPF, asbestosis and mesothelioma.
Asbestosis is the name given to the lung disease developed by people with a known history of exposure to asbestos. The symptoms and presentation of this disease can be identical to IPF; the only difference between the two diseases is whether a patient knows about their exposure to asbestos. People with asbestosis are not currently eligible for new treatments for IPF, despite the fact that these treatments work on curing an identical disease.
Researchers have suggested that a proportion of IPF may be due to unknown exposure to asbestos. They analysed mortality rates for IPF, asbestosis and mesothelioma across England and Wales. Data were obtained from the Office of National Statistics on the annual number of deaths due to IPF, mesothelioma and asbestos for the period 1974–2012, broken down by age, sex and region.
The analysis revealed national and regional correlations between the three diseases, which supports the theory that a proportion of IPF cases are due to unknown exposure to asbestos. If this asbestos exposure was known, it would be likely that these patients were diagnosed with asbestosis rather than IPF.
There were also high rates of IPF deaths in particular regions in the North West and South East of England, which has a history of shipyard work and therefore potential exposure to asbestos dust.
Lead researcher, Dr Carl Reynolds from Imperial College London, said: "The findings are consistent with the hypothesis that a proportion of IPF cases are likely to be caused by unknown exposure to asbestos. More research is needed in this area, particularly as patients known to have asbestos exposure are not currently considered to be candidates for new treatments for IPF and this may be inappropriate."
Lauren Anderson | Eurek Alert!
Live probiotics can re-balance the gut microbiome and modify immune system response
20.11.2018 | Symprove
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.
Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
19.11.2018 | Event News
09.11.2018 | Event News
06.11.2018 | Event News
20.11.2018 | Life Sciences
20.11.2018 | Life Sciences
20.11.2018 | Physics and Astronomy