The most recent research released in June's Journal of Thoracic Oncology says video assisted thoracic surgery (VATS) is a valuable tool in managing lesions detected in a lung cancer screening program. The primary objective of lung cancer screening with low dose computer tomography (CT) is to detect lung cancer at an early stage and thus amenable to a complete surgical resection, the only established cure for lung cancer.
Lung cancer currently has no standard screening program and less than one third of lung cancer patients present with early stage disease amenable to cure. One of the concerns regarding lung cancer screening is how to manage detected lung nodules, the majority of which are benign.
The Danish study, presented in the June 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, evaluated the role of VATS resection in a CT screened (2,052) versus unscreened (2,052) high risk Danish population from the Danish Lung Cancer Screening Trial. The study is a randomized clinically controlled trial comparing 5 annual CT screening rounds with no screening in 4104 individuals.
Sixty-eight (3.3%) lung cancers were detected in the screened population versus 24 (1.2%) in the unscreened population. Fifty-one of the 68 patients with lung cancer in the screened group were candidates for surgery for cure and 84 percent of these had VATS versus 50 percent in the unscreened group. Eight patients in the screened group had lesions highly suspicious for cancer that proved to be benign once removed by VATS.
Although the comparison groups were too small to detect a difference in this study, previous studies have found VATS to confer advantages over thoracotomy with respect to reduced post-operative pain, shorter hospital stay, more rapid resumption of normal daily activities, less impairment in pulmonary function, less impairment in shoulder function, reduced cytokine release, decreased time to initiation of adjuvant chemotherapy, lower incidence of complications and economic advantages. Thus, the ability to perform VATS, compared to thoracotomy, more frequently in the screened versus unscreened population, is potentially a very significant finding.
"We believe that it is of upmost importance for future low dose CT screening trials to have thoracic surgeons involved in the early detection program and that the thoracic surgeons should have a dedicated VATS program," the authors say.
The lead author of this work is Dr. Rene Petersen. Dr. Jesper Pedersen is co-author of the article and an IASLC member.About the IASLC:
Kristal Griffith | EurekAlert!
NIH scientists combine technologies to view the retina in unprecedented detail
14.11.2018 | NIH/National Eye Institute
Medica 2018: New software for a more efficient planning of minimally invasive surgery
06.11.2018 | Technische Universität Kaiserslautern
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
14.11.2018 | Materials Sciences
14.11.2018 | Health and Medicine
14.11.2018 | Life Sciences