Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Video-assisted thoracic surgery valuable tool in lung cancer screening

16.05.2012
CT screening of high-risk Danish population yields higher incidence of early stage lung cancer amenable to VATS resections

The most recent research released in June's Journal of Thoracic Oncology says video assisted thoracic surgery (VATS) is a valuable tool in managing lesions detected in a lung cancer screening program. The primary objective of lung cancer screening with low dose computer tomography (CT) is to detect lung cancer at an early stage and thus amenable to a complete surgical resection, the only established cure for lung cancer.

Lung cancer currently has no standard screening program and less than one third of lung cancer patients present with early stage disease amenable to cure. One of the concerns regarding lung cancer screening is how to manage detected lung nodules, the majority of which are benign.

The Danish study, presented in the June 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, evaluated the role of VATS resection in a CT screened (2,052) versus unscreened (2,052) high risk Danish population from the Danish Lung Cancer Screening Trial. The study is a randomized clinically controlled trial comparing 5 annual CT screening rounds with no screening in 4104 individuals.

Sixty-eight (3.3%) lung cancers were detected in the screened population versus 24 (1.2%) in the unscreened population. Fifty-one of the 68 patients with lung cancer in the screened group were candidates for surgery for cure and 84 percent of these had VATS versus 50 percent in the unscreened group. Eight patients in the screened group had lesions highly suspicious for cancer that proved to be benign once removed by VATS.

Although the comparison groups were too small to detect a difference in this study, previous studies have found VATS to confer advantages over thoracotomy with respect to reduced post-operative pain, shorter hospital stay, more rapid resumption of normal daily activities, less impairment in pulmonary function, less impairment in shoulder function, reduced cytokine release, decreased time to initiation of adjuvant chemotherapy, lower incidence of complications and economic advantages. Thus, the ability to perform VATS, compared to thoracotomy, more frequently in the screened versus unscreened population, is potentially a very significant finding.

"We believe that it is of upmost importance for future low dose CT screening trials to have thoracic surgeons involved in the early detection program and that the thoracic surgeons should have a dedicated VATS program," the authors say.

The lead author of this work is Dr. Rene Petersen. Dr. Jesper Pedersen is co-author of the article and an IASLC member.

About the IASLC:

The International Association for the Study of Lung Cancer (IASLC) is the only global organization dedicated to the study of lung cancer. Founded in 1974, the association's membership includes more than 3,500 lung cancer specialists in 80 countries. To learn more about IASLC please visit www.iaslc.org.

Kristal Griffith | EurekAlert!
Further information:
http://www.iaslc.org

More articles from Medical Engineering:

nachricht Faster detection of atrial fibrillation thanks to smartwatch
18.03.2019 | Universität Greifswald

nachricht A peek into lymph nodes
15.03.2019 | Tohoku University

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The taming of the light screw

DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.

The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...

Im Focus: Magnetic micro-boats

Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.

The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...

Im Focus: Self-healing coating made of corn starch makes small scratches disappear through heat

Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.

Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

Im Focus: Heading towards a tsunami of light

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.

"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Laser processing is a matter for the head – LZH at the Hannover Messe 2019

25.03.2019 | Trade Fair News

A Varied Menu

25.03.2019 | Life Sciences

‘Time Machine’ heralds new era

25.03.2019 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>