Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Scientists have spotted new compounds with herbicidal potential from sea fungus


Scientists of Far Eastern Federal University (FEFU) and the G.B. Elyakov Pacific Institute of Bioorganic Chemistry (FEB RAS) together with German colleagues spotted six new and three already known biologically active compounds in a new strain of the fungus Penicillium piltunense first time isolated. One compound has a pronounced anti-inflammatory activity, others have herbicidal potential, i.e., possibly, can become components of new chemicals for weed control. A related study is published in Marine Drugs.

The spotted compounds are the derivatives of aspterric acid which herbicidal activity was previously highlighted in a scientific report published in Nature journal. The authors of the report noted that the acid has a mediocre ability to inhibit plant growth, suggested its analogs promise to be more effective.

A new strain of the fungus Penicillium piltunense first time isolated from sea soil collected near the northeast shelf of the Sakhalin Island, The Sea of Okhotsk.

Credit: FEFU press office

"We believe that the compounds isolated could potentially have herbicidal activity since they are the very analogs of aspterric acid, which our foreign colleagues wrote about in Nature. We have not yet been able to check how strongly these properties are expressed in the substances found, but we plan to find it out further. Worth noting, the new herbicidal compounds have not been introduced onto the market for about 30 years", said Olesya Zhuravleva, Ph.D., Head of the Laboratory of Biologically Active Compounds, FEFU School of Natural Sciences.

The scientist went on that one of the compounds has a pronounced anti-inflammatory activity confirmed by an experiment on macrophage cell lines of mice. In the future, new substances can be useful to the developing of anti-inflammatory drugs.

Scientists are also planning to test all the compounds obtained for antimicrobial activity. If it confirms, the compounds will also become candidates for the development of new antibiotics.

Fungi of the genus Penicillium are one of the most common fungus species on our planet. They grow both on land and in the ocean, where they are associated with seagrass, algae, soil, vertebrate and invertebrate animals.

The previously unknown strain of the fungus Penicillium piltunense KMM4648 was isolated from sea soil collected near the northeast shelf of the Sakhalin Island, The Sea of Okhotsk during a marine expedition on the "Akademik Oparin" research vessel. The strain was described by mycologists of the Laboratory of Microbiology PIBOC FEB RAS, Dr. Mikhail V. Pivkin and Dr. Natalya Kirichuk.

Subsequently, the fungal strain was investigated by researchers of the Laboratory of Biologically Active Compounds of the FEFU School of Natural Sciences, together with colleagues from the Laboratory of Microbial Metabolites of the PIBOC FEB RAS.


The study was supported by a grant from the Russian Science Foundation No. 19-74-10014 ("Micromycetes marine fungus are a promising source of bioactive molecules", managed by Olesya Zhuravleva, Ph.D.)

Alexander Zverev | EurekAlert!
Further information:

More articles from Life Sciences:

nachricht New self-assembled monolayer is resistant to air
22.01.2020 | University of Groningen

nachricht Mosquitoes are drawn to flowers as much as people -- and now scientists know why
22.01.2020 | University of Washington

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New roles found for Huntington's disease protein

Crucial role in synapse formation could be new avenue toward treatment

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative...

Im Focus: A new look at 'strange metals'

For years, a new synthesis method has been developed at TU Wien (Vienna) to unlock the secrets of "strange metals". Now a breakthrough has been achieved. The results have been published in "Science".

Superconductors allow electrical current to flow without any resistance - but only below a certain critical temperature. Many materials have to be cooled down...

Im Focus: Programmable nests for cells

KIT researchers develop novel composites of DNA, silica particles, and carbon nanotubes -- Properties can be tailored to various applications

Using DNA, smallest silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) developed novel programmable materials....

Im Focus: Miniature double glazing: Material developed which is heat-insulating and heat-conducting at the same time

Styrofoam or copper - both materials have very different properties with regard to their ability to conduct heat. Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz and the University of Bayreuth have now jointly developed and characterized a novel, extremely thin and transparent material that has different thermal conduction properties depending on the direction. While it can conduct heat extremely well in one direction, it shows good thermal insulation in the other direction.

Thermal insulation and thermal conduction play a crucial role in our everyday lives - from computer processors, where it is important to dissipate heat as...

Im Focus: Fraunhofer IAF establishes an application laboratory for quantum sensors

In order to advance the transfer of research developments from the field of quantum sensor technology into industrial applications, an application laboratory is being established at Fraunhofer IAF. This will enable interested companies and especially regional SMEs and start-ups to evaluate the innovation potential of quantum sensors for their specific requirements. Both the state of Baden-Württemberg and the Fraunhofer-Gesellschaft are supporting the four-year project with one million euros each.

The application laboratory is being set up as part of the Fraunhofer lighthouse project »QMag«, short for quantum magnetometry. In this project, researchers...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

11th Advanced Battery Power Conference, March 24-25, 2020 in Münster/Germany

16.01.2020 | Event News

Laser Colloquium Hydrogen LKH2: fast and reliable fuel cell manufacturing

15.01.2020 | Event News

„Advanced Battery Power“- Conference, Contributions are welcome!

07.01.2020 | Event News

Latest News

New self-assembled monolayer is resistant to air

22.01.2020 | Life Sciences

Ultrafast camera takes 1 trillion frames per second of transparent objects and phenomena

22.01.2020 | Power and Electrical Engineering

Mosquitoes are drawn to flowers as much as people -- and now scientists know why

22.01.2020 | Life Sciences

Science & Research
Overview of more VideoLinks >>>