Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New species of infectious disease found in Amazon

03.04.2008
While investigating the tropical disease leptospirosis in the Peruvian Amazon, an infectious disease specialist from the University of California, San Diego School of Medicine has uncovered new, emerging bacteria that may be responsible for up to 40 percent of cases of the disease. Patients with severe forms of leptospirosis have jaundice, renal failure and lung hemorrhage, with high fatality rates.

Joseph Vinetz, M.D., professor of medicine in UC San Diego’s Division of Infectious Diseases – working in collaboration with colleagues from Universidad Peruana Cayetano Heredia in Lima, Peru, and others – headed the study that led to discovery of the new species in the family of pathogens, Leptospira, which is spread from animals to humans. The findings will be published in the April 1 issue of the Public Library of Science (PLoS) journal Neglected Tropical Diseases.

Leptospirosis is a severe, water-borne disease transmitted from animals to humans, with tens of millions of human cases worldwide each year. Fatality rates can range as high as 20 to 25 percent in some regions, and it is particularly prevalent in tropical countries where poor people live under highly crowded condition, or in rural areas where people are exposed to water contaminated by the urine of Leptospira-infected animals such as rats.

The new species reflects Amazonian biodiversity, according to Vinetz, and the pathogen has apparently evolved to become an important cause of leptospirosis in the Peruvian Amazon region of Iquitos. There, Vinetz leads an international team of physicians from the U.S. and Peru in an NIH-funded training program studying malaria, leptospirosis and other infectious diseases that impact disadvantaged populations in developing countries.

... more about:
»Amazon »Infectious »Vinetz »leptospirosis »species »strain

The researchers found that the new species, Leptospira licerasiae – cultured from a very small number of patients, as well as eight rats – is significantly different from other forms of the bacteria at a genomic level and has novel biological features.

“This strain has fundamentally different characteristics,” said Vinetz, adding that the next step is to sequence its genome. “We think that hundreds of patients are infected with this pathogen, which is so unique that antibodies for the disease don’t react to the regular tests for leptospirosis.”

In testing 881 patients in a prospective clinical study of fever, the researchers found that 41 percent of them had antibodies that reacted only to this new strain of the bacteria, showing a much higher incidence of leptospirosis than previously suspected.

“This observation is relevant to other regions of the world where leptospirosis is likely to be common, because it’s necessary to identify the right strain of the Lepstospira in order to make the correct diagnosis,” Vinetz said.

Since isolation of the new Leptospira in people was rare despite the high prevalence of antibodies to this strain of the bacteria in the Amazonian population, Vinetz theorizes that the individuals with positive cultures may have a previously undiscovered immune system defect, making them more susceptible to the disease.

Debra Kain | EurekAlert!
Further information:
http://www.ucsd.edu

Further reports about: Amazon Infectious Vinetz leptospirosis species strain

More articles from Life Sciences:

nachricht If Machines Could Smell ...
19.07.2019 | Fraunhofer-Institut für Produktionstechnik und Automatisierung IPA

nachricht Algae-killing viruses spur nutrient recycling in oceans
18.07.2019 | Rutgers University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Better thermal conductivity by adjusting the arrangement of atoms

Adjusting the thermal conductivity of materials is one of the challenges nanoscience is currently facing. Together with colleagues from the Netherlands and Spain, researchers from the University of Basel have shown that the atomic vibrations that determine heat generation in nanowires can be controlled through the arrangement of atoms alone. The scientists will publish the results shortly in the journal Nano Letters.

In the electronics and computer industry, components are becoming ever smaller and more powerful. However, there are problems with the heat generation. It is...

Im Focus: First-ever visualizations of electrical gating effects on electronic structure

Scientists have visualised the electronic structure in a microelectronic device for the first time, opening up opportunities for finely-tuned high performance electronic devices.

Physicists from the University of Warwick and the University of Washington have developed a technique to measure the energy and momentum of electrons in...

Im Focus: Megakaryocytes act as „bouncers“ restraining cell migration in the bone marrow

Scientists at the University Würzburg and University Hospital of Würzburg found that megakaryocytes act as “bouncers” and thus modulate bone marrow niche properties and cell migration dynamics. The study was published in July in the Journal “Haematologica”.

Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood cells: red...

Im Focus: Artificial neural network resolves puzzles from condensed matter physics: Which is the perfect quantum theory?

For some phenomena in quantum many-body physics several competing theories exist. But which of them describes a quantum phenomenon best? A team of researchers from the Technical University of Munich (TUM) and Harvard University in the United States has now successfully deployed artificial neural networks for image analysis of quantum systems.

Is that a dog or a cat? Such a classification is a prime example of machine learning: artificial neural networks can be trained to analyze images by looking...

Im Focus: Extremely hard yet metallically conductive: Bayreuth researchers develop novel material with high-tech prospects

An international research group led by scientists from the University of Bayreuth has produced a previously unknown material: Rhenium nitride pernitride. Thanks to combining properties that were previously considered incompatible, it looks set to become highly attractive for technological applications. Indeed, it is a super-hard metallic conductor that can withstand extremely high pressures like a diamond. A process now developed in Bayreuth opens up the possibility of producing rhenium nitride pernitride and other technologically interesting materials in sufficiently large quantity for their properties characterisation. The new findings are presented in "Nature Communications".

The possibility of finding a compound that was metallically conductive, super-hard, and ultra-incompressible was long considered unlikely in science. It was...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on UV LED Technologies & Applications – ICULTA 2020 | Call for Abstracts

24.06.2019 | Event News

SEMANTiCS 2019 brings together industry leaders and data scientists in Karlsruhe

29.04.2019 | Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

 
Latest News

Heat flow through single molecules detected

19.07.2019 | Physics and Astronomy

Heat transport through single molecules

19.07.2019 | Physics and Astronomy

Welcome Committee for Comets

19.07.2019 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>