Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cells from the Research Institute of the MUHC on the road to China

27.03.2008
The diabetes epidemic is devastating many areas of the world. In China, approximately 20 million people suffer from the disease - and the number keeps growing. To meet this massive health challenge, the Chinese government is encouraging researchers from all over the world to collaborate with Chinese scientists in the development of effective diabetes therapies.

To fund an innovative Quebec-Chinese research initiative in this area, the Ministère du Développement économique, de l'Innovation et de l'Exportation from Quebec recently awarded a grant of $150,000 to Dr. Constantin Polychronakos of the Research Institute of the McGill University Health Centre (MUHC) in Montreal.

The funding will be used to establish a partnership with Dr. Du, Director of the Pharmacology Institute of the Chinese Academy of Medical Sciences in Beijing. The collaboration will focus on a new therapeutic approach to preventing type 2 diabetes.

Contrary to popular belief, the pancreas is not the only insulin-producing organ of the body. The thymus also produces a small quantity of insulin. While insufficient to regulate blood glucose levels, this insulin "programs" the immune system to recognize the peptide as "self." In healthy people, this programming prevents pancreatic insulin from being destroyed by an immune reaction. Dr. Polychronakos has studied this mechanism for many years and has succeeded in creating a culture line of insulin-producing thymus cells.

... more about:
»Diabetes »Hospital »Insulin »Montreal »Polychronakos

His goal is to find a drug that would trigger these cells to secrete more insulin. This would theoretically increase the body's tolerance to the hormone and thus reduce the symptoms of diabetes. However, achieving this objective means testing approximately 100,000 different compounds with special high-performance drug screening equipment-precisely the technology that is available in Dr. Du's laboratory in Beijing.

The collaboration between Dr. Polychronakos and Dr. Du will allow each one to benefit from the other's technology. Their research initiative has enormous potential and international scope. The project is expected to get underway no later than fall, 2008.

Dr. Constantin Polychronakos is Director of the MUHC's Pediatric Endocrinology and Metabolism Division, Co-Leader of the Endocrinology, Diabetes, Nutrition and Kidney Diseases Axes of the Research Institute of the MUHCand Professor of Pediatrics and Human Genetics at McGill University.

This project is co-funded by the Ministère du Développement économique, de l'Innovation et de l'Exportation, the Juvenile Diabetes Research Foundation, and the Government of the People's Republic of China.

The McGill University Health Centre (MUHC) is a comprehensive academic health institution with an international reputation for excellence in clinical programs, research and teaching. The MUHC is a merger of five teaching hospitals affiliated with the Faculty of Medicine at McGill University--the Montreal Children's, Montreal General, Royal Victoria, and Montreal Neurological Hospitals, as well as the Montreal Chest Institute. Building on the tradition of medical leadership of the founding hospitals, the goal of the MUHC is to provide patient care based on the most advanced knowledge in the health care field, and to contribute to the development of new knowledge. www.muhc.ca

The Research Institute of the McGill University Health Centre (RI MUHC) is a world-renowned biomedical and health-care hospital research centre. Located in Montreal, Quebec, the institute is the research arm of the MUHC, the university health center affiliated with the Faculty of Medicine at McGill University. The institute supports over 600 researchers, nearly 1200 graduate and post-doctoral students and operates more than 300 laboratories devoted to a broad spectrum of fundamental and clinical research. The Research Institute operates at the forefront of knowledge, innovation and technology and is inextricably linked to the clinical programs of the MUHC, ensuring that patients benefit directly from the latest research-based knowledge.
The Research Institute of the MUHC is supported in part by the Fonds de la recherche en santé du Québec.

For further details visit: www.muhc.ca/research.

The Montreal Children's Hospital is the pediatric teaching hospital of the McGill University Health Centre (MUHC). The institution is a leader in the care and treatment of sick infants, children, and adolescents from across Quebec. The Montreal Children's Hospital provides a high level and broad scope of health care services, and provides ultra specialized care in many fields including: cardiology and cardiac surgery; neurology and neurosurgery, traumatology; genetic research; psychiatry and child development and musculoskeletal conditions, including orthopedics and rheumatology. Fully bilingual and multicultural, the institution respectfully serves an increasingly diverse community in more than 50 languages. www.thechildren.com

For more information please contact:

Isabelle Kling
Communications Coordinator (research)
MUHC Public Relations and Communications
(514) 934-1934 #36419
isabelle.kling@muhc.mcgill.ca

Isabelle Kling | MUHC
Further information:
http://www.muhc.ca/research
http://www.thechildren.com

Further reports about: Diabetes Hospital Insulin Montreal Polychronakos

More articles from Life Sciences:

nachricht Microbes can grow on nitric oxide (NO)
18.03.2019 | Max-Planck-Institut für Marine Mikrobiologie

nachricht Novel methods for analyzing neural circuits for innate behaviors in insects
15.03.2019 | Kanazawa University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Revealing the secret of the vacuum for the first time

New research group at the University of Jena combines theory and experiment to demonstrate for the first time certain physical processes in a quantum vacuum

For most people, a vacuum is an empty space. Quantum physics, on the other hand, assumes that even in this lowest-energy state, particles and antiparticles...

Im Focus: Sussex scientists one step closer to a clock that could replace GPS and Galileo

Physicists in the EPic Lab at University of Sussex make crucial development in global race to develop a portable atomic clock

Scientists in the Emergent Photonics Lab (EPic Lab) at the University of Sussex have made a breakthrough to a crucial element of an atomic clock - devices...

Im Focus: Sensing shakes

A new way to sense earthquakes could help improve early warning systems

Every year earthquakes worldwide claim hundreds or even thousands of lives. Forewarning allows people to head for safety and a matter of seconds could spell...

Im Focus: A thermo-sensor for magnetic bits

New concept for energy-efficient data processing technology

Scientists of the Department of Physics at the University of Hamburg, Germany, detected the magnetic states of atoms on a surface using only heat. The...

Im Focus: The moiré patterns of three layers change the electronic properties of graphene

Combining an atomically thin graphene and a boron nitride layer at a slightly rotated angle changes their electrical properties. Physicists at the University of Basel have now shown for the first time the combination with a third layer can result in new material properties also in a three-layer sandwich of carbon and boron nitride. This significantly increases the number of potential synthetic materials, report the researchers in the scientific journal Nano Letters.

Last year, researchers in the US caused a big stir when they showed that rotating two stacked graphene layers by a “magical” angle of 1.1 degrees turns...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Researchers measure near-perfect performance in low-cost semiconductors

18.03.2019 | Power and Electrical Engineering

Nanocrystal 'factory' could revolutionize quantum dot manufacturing

18.03.2019 | Materials Sciences

Long-distance quantum information exchange -- success at the nanoscale

18.03.2019 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>