To fund an innovative Quebec-Chinese research initiative in this area, the Ministère du Développement économique, de l'Innovation et de l'Exportation from Quebec recently awarded a grant of $150,000 to Dr. Constantin Polychronakos of the Research Institute of the McGill University Health Centre (MUHC) in Montreal.
The funding will be used to establish a partnership with Dr. Du, Director of the Pharmacology Institute of the Chinese Academy of Medical Sciences in Beijing. The collaboration will focus on a new therapeutic approach to preventing type 2 diabetes.
Contrary to popular belief, the pancreas is not the only insulin-producing organ of the body. The thymus also produces a small quantity of insulin. While insufficient to regulate blood glucose levels, this insulin "programs" the immune system to recognize the peptide as "self." In healthy people, this programming prevents pancreatic insulin from being destroyed by an immune reaction. Dr. Polychronakos has studied this mechanism for many years and has succeeded in creating a culture line of insulin-producing thymus cells.
His goal is to find a drug that would trigger these cells to secrete more insulin. This would theoretically increase the body's tolerance to the hormone and thus reduce the symptoms of diabetes. However, achieving this objective means testing approximately 100,000 different compounds with special high-performance drug screening equipment-precisely the technology that is available in Dr. Du's laboratory in Beijing.
The collaboration between Dr. Polychronakos and Dr. Du will allow each one to benefit from the other's technology. Their research initiative has enormous potential and international scope. The project is expected to get underway no later than fall, 2008.
Dr. Constantin Polychronakos is Director of the MUHC's Pediatric Endocrinology and Metabolism Division, Co-Leader of the Endocrinology, Diabetes, Nutrition and Kidney Diseases Axes of the Research Institute of the MUHCand Professor of Pediatrics and Human Genetics at McGill University.
This project is co-funded by the Ministère du Développement économique, de l'Innovation et de l'Exportation, the Juvenile Diabetes Research Foundation, and the Government of the People's Republic of China.
The McGill University Health Centre (MUHC) is a comprehensive academic health institution with an international reputation for excellence in clinical programs, research and teaching. The MUHC is a merger of five teaching hospitals affiliated with the Faculty of Medicine at McGill University--the Montreal Children's, Montreal General, Royal Victoria, and Montreal Neurological Hospitals, as well as the Montreal Chest Institute. Building on the tradition of medical leadership of the founding hospitals, the goal of the MUHC is to provide patient care based on the most advanced knowledge in the health care field, and to contribute to the development of new knowledge. www.muhc.caThe Research Institute of the McGill University Health Centre (RI MUHC) is a world-renowned biomedical and health-care hospital research centre. Located in Montreal, Quebec, the institute is the research arm of the MUHC, the university health center affiliated with the Faculty of Medicine at McGill University. The institute supports over 600 researchers, nearly 1200 graduate and post-doctoral students and operates more than 300 laboratories devoted to a broad spectrum of fundamental and clinical research. The Research Institute operates at the forefront of knowledge, innovation and technology and is inextricably linked to the clinical programs of the MUHC, ensuring that patients benefit directly from the latest research-based knowledge.
For further details visit: www.muhc.ca/research.
The Montreal Children's Hospital is the pediatric teaching hospital of the McGill University Health Centre (MUHC). The institution is a leader in the care and treatment of sick infants, children, and adolescents from across Quebec. The Montreal Children's Hospital provides a high level and broad scope of health care services, and provides ultra specialized care in many fields including: cardiology and cardiac surgery; neurology and neurosurgery, traumatology; genetic research; psychiatry and child development and musculoskeletal conditions, including orthopedics and rheumatology. Fully bilingual and multicultural, the institution respectfully serves an increasingly diverse community in more than 50 languages. www.thechildren.com
For more information please contact:Isabelle Kling
Turning carbon dioxide into liquid fuel
06.08.2020 | DOE/Argonne National Laboratory
Tellurium makes the difference
06.08.2020 | Friedrich-Schiller-Universität Jena
Scientists at the Fraunhofer Institute for Laser Technology ILT have come up with a striking new addition to contact stamping technologies in the ERDF research project ScanCut. In collaboration with industry partners from North Rhine-Westphalia, the Aachen-based team of researchers developed a hybrid manufacturing process for the laser cutting of thin-walled metal strips. This new process makes it possible to fabricate even the tiniest details of contact parts in an eco-friendly, high-precision and efficient manner.
Plug connectors are tiny and, at first glance, unremarkable – yet modern vehicles would be unable to function without them. Several thousand plug connectors...
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health.
Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women...
Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only...
“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.
Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...
An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.
Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...
23.07.2020 | Event News
21.07.2020 | Event News
07.07.2020 | Event News
06.08.2020 | Earth Sciences
06.08.2020 | Power and Electrical Engineering
06.08.2020 | Life Sciences