Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

BGI reports the completed sequence of foxtail millet genome

14.05.2012
The latest study was published online in Nature Biotechnology
BGI, the world's largest genomics organization, in cooperation with Zhangjiakou Academy of Agricultural Science, has completed the genome sequence and analysis of foxtail millet (Setaria italica), the second-most widely planted species of millet. This study provides an invaluable resource for the study and genetic improvement of foxtail millet and millet crops at a genome-wide level. Results of the latest study were published online today in Nature Biotechnology.

Foxtail millet is an important cereal crop providing food and feed in semi-arid areas. It is the top-one crop in ancient China. It promises to serve as an important model for comparative genomics and functional gene studies, due to its small genome size (~490M), self-pollination, rich genetic diversity (~6000 varieties), complete collection of germplasm, and the availability of efficient transformation platforms. It is also evolutionarily close to several important biofuel grasses, such as switchgrass and napier grass.

"The lower yield of traditional cultivars has largely limited cultivation and utilization of foxtail millet." said Dr. Gengyun Zhang, Vice President of BGI. "Hybrid cultivars, recently developed by Professor Zhihai Zhao in Zhangjiakou Agricultural Academy of Science, doubled the yield of foxtail millet. I expect that the results of this study could set an example of applying the genome sequence to better understanding and quicker developing new varieties of a neglected crop with higher yield, better grain quality and stress tolerance."

In this study, researchers from BGI carried out next-generation sequencing and de novo assembly for "Zhang gu", one strain of foxtail millet from Northern China. The final genome assembly was 423 Mb, and 38,801 protein-coding genes have been predicted, of which ~81% were expressed. They also developed a high density genetic linkage map using a set of genetic markers identified by resequencing another strain named "A2" and an F2 population of "Zhang gu" crossing A2. A2 is the widely used female strain of hybrid foxtail millet.

Comparing the foxtail millet genome and rice genome, researchers found the rules and changing tendency of the foxtail millet chromosomes, which are important for understanding the millet genome evolution. "We found nine foxtail millet chromosomes were formed after three chromosomal reshuffling events." said Dr. Zhang, "Of the three events, two occurred after divergence of foxtail millet from rice, followed by a specific reshuffling after divergence of millet from sorghum."

C4 plants are better adapted than C3 plants in environments with higher daytime temperature, intense sunlight, drought, or nitrogen or CO2 limitation. Foxtail millet is a diploid C4 panicoid crop species. With its genome available, researchers comprehensively analyzed the evolution of several key genes in C4 photosynthesis pathway. Results indicated that all the genes involved in C4 carbon fixation pathway also existed in C3 plants. Thus, researchers predicted that the emergence of C4 pathway could result from expressional and/or functional modifications of these genes.

The genome sequence of foxtail millet could facilitate mapping of quantitative trait loci. In this study, researchers used the foxtail millet genome to aid identification of herbicide resistant genes, and they accurately identified the gene for sethoxydim resistance.

"The decoding of whole genome sequence is an essential and important step to reveal the secrets of genetic control of crops, which could serve as an important platform for biological studies and breeding. " added by Dr. Zhang.

About BGI

BGI was founded in Beijing, China on September 9th, 1999 with the mission of being a premier scientific partner to the global research community. The goal of BGI is to make leading-edge genomic science highly accessible through its investment in infrastructure that leverages the best available technology, economies of scale, and expert bioinformatics resources. BGI, and its affiliates, BGI Americas, based in Cambridge, MA and BGI Europe, based in Copenhagen. Denmark, have established partnerships and collaborations with leading academic and government research institutions as well as global biotechnology and pharmaceutical companies, supporting a variety of disease, agricultural, environmental, and related applications.

BGI has established a proven track record of excellence, delivering results with high efficiency and accuracy for innovative, high-profile research which has generated over 170 publications in top-tier journals such as Nature and Science. These accomplishments include sequencing one percent of the human genome for the International Human Genome Project, contributing 10 percent to the International Human HapMap Project, carrying out research to combat SARS and German deadly E. coli, playing a key role in the Sino-British Chicken Genome Project, and completing the sequence of the rice genome, the silkworm genome, the first Asian diploid genome, the potato genome, and, most recently, 1000 genomes and human Gut metagenome. For more information about BGI, please visit www.genomics.cn.

Contact Information:

Gengyun Zhang
Vice President
BGI
zhanggengyun@genomics.cn
Bicheng Yang
Public Communication Officer
BGI
+86-755-82639701
yangbicheng@genomics.cn

Jia Liu | EurekAlert!
Further information:
http://www.genomics.cn

More articles from Life Sciences:

nachricht First use of vasoprotective antibody in cardiogenic shock
17.05.2019 | Deutsches Zentrum für Herz-Kreislauf-Forschung e.V.

nachricht A nerve cell serves as a “single” for studies
15.05.2019 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Self-repairing batteries

UTokyo engineers develop a way to create high-capacity long-life batteries

Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...

Im Focus: Quantum Cloud Computing with Self-Check

With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.

Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...

Im Focus: Accelerating quantum technologies with materials processing at the atomic scale

'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.

However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...

Im Focus: A step towards probabilistic computing

Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future

When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...

Im Focus: Recording embryonic development

Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells

The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

SEMANTiCS 2019 brings together industry leaders and data scientists in Karlsruhe

29.04.2019 | Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

 
Latest News

Discovering unusual structures from exception using big data and machine learning techniques

17.05.2019 | Materials Sciences

ALMA discovers aluminum around young star

17.05.2019 | Physics and Astronomy

A new iron-based superconductor stabilized by inter-block charger transfer

17.05.2019 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>