Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cow’s resistance to worms is genetically determined

10.10.2003


Research carried out in the Netherlands has revealed that the genetic background of cattle apparently determines how quickly and effectively they acquire immunity to infections from gastrointestinal worms. Such infections cause considerable economic losses in the beef farming industry. During her doctoral research, Kirezi Kanobana investigated how cattle rid themselves of worms and prevent new infections.



Kanobana used an infection model in which, based on their genetic background, animals exhibited varying degrees of resistance to gastrointestinal worms. Broadly speaking there are three groups of animals. Two percent of the animals are naturally immune to a first infection. Another group reacts to the first infection with an effective immune response. In the event of a second infection these animals are protected. A third group is highly sensitive for infection and scarcely acquires any immunity even after repeated infections.

The researcher distinguished the three groups of animals by using two types of measurement. Three-month-old calves were infected with 100,000 larvae of a small-intestinal worm. After the infection an initial distinction was made on the basis of parasitological variables such as worm counts and the detection of eggs in the animals’ excreta. Secondly, immunological parameters were used to confirm the three groups of animals.


In an animal that has no resistance to a worm infection, the worms occur in the first part of the small intestine. In animals that develop resistance, worms are translocated towards the end of the small intestine.

Interestingly the male worms disappear out of the intestine first, followed by the female worms. This conclusion is based on a study six different parts of the small intestine, which in calves has a length of between 25 to 40 metres. In addition to this, Kanobana also discovered a number of mechanisms that are responsible for ensuring the disappearance of the worms from the small intestine.

Cattle pick up larvae from the grass, which develop into adult worms in the cattle’s gastrointestinal system. The worms reproduce sexually and lay eggs. The eggs pass out of the cattle with the excreta. In the dung, the eggs can once more develop into larvae. In this manner cattle can continually be reinfected by eating the grass.

Preventative anti-worm drugs are effective but are a potential risk to public health, as they are sometimes found in dairy and meat products. An understanding of how cattle acquire immunity might contribute to the development of a vaccine, which would be a good alternative for preventing gastrointestinal worm infections.

Sonja Jacobs | alfa
Further information:
http://www.nwo.nl

More articles from Agricultural and Forestry Science:

nachricht New research recovers nutrients from seafood process water
31.10.2018 | Chalmers University of Technology

nachricht Plant Hormone Makes Space Farming a Possibility
17.10.2018 | Universität Zürich

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

Im Focus: Coping with errors in the quantum age

Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly

The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Massive impact crater from a kilometer-wide iron meteorite discovered in Greenland

15.11.2018 | Earth Sciences

When electric fields make spins swirl

15.11.2018 | Physics and Astronomy

Discovery of a cool super-Earth

15.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>