Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Virus detector harnesses ring of light in 'whispering gallery mode'

24.08.2012
By affixing nanoscale gold spheres onto a microscopic bead of glass, researchers have created a super-sensor that can detect even single samples of the smallest known viruses. The sensor uses a peculiar behavior of light known as "whispering gallery mode," named after the famous circular gallery in St. Paul's Cathedral in London, where a whisper near the wall can be heard around the gallery.

In a similar way, waves of light are sent whirling around the inside of a small glass bead, resonating at a specific frequency. Just as a small object on a vibrating violin string can change its frequency – ever so slightly – so too can a virus landing on the sensor change the resonant frequency of the light.

With the initial glass sphere, researchers were able to detect changes in frequency from viruses about the size of influenza, a relatively large virus. The system, however, was not sensitive enough to detect anything smaller, such as the Polio virus.

The researchers were able to increase the sensitivity of the device nearly seventyfold by adding gold nanospheres to the surface of the glass, which created what the researchers referred to as "plasmonic hot spots" – areas where the light waves coupled with waves of electrons. This hybrid sensor not only detected the presence of the MS2 virus – the current light-weight in the world of RNA viruses – it also was able to determine the weight of the virus by measuring the precise frequency change of the light. With a few minor adjustments, the sensor should also be able to detect single proteins, such as cancer markers that appear in the blood long before outward signs of cancer can be detected.

The results were published in the American Institute of Physics (AIP) journal Applied Physics Letters.

Article: "Taking whispering gallery-mode single virus detection and sizing to the limit" is published in Applied Physics Letters.

Link: http://apl.aip.org/resource/1/applab/v101/i4/p043704_s1

Authors: V.R. Dantham (1), S. Holler (1,2) , V. Kochenko (3) , Z. Wan (4), and S. Arnold (1)

(1) Polytechnic Institute of New York University, Brooklyn New York
(2) Fordham University, Bronx, New York
(3) New York City College of Technology, Brooklyn, New York

Charles Blue | EurekAlert!
Further information:
http://www.aip.org

More articles from Physics and Astronomy:

nachricht Astronomers find unexpected, dust-obscured star formation in distant galaxy
24.03.2017 | University of Massachusetts at Amherst

nachricht Gravitational wave kicks monster black hole out of galactic core
24.03.2017 | NASA/Goddard Space Flight Center

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Northern oceans pumped CO2 into the atmosphere

27.03.2017 | Earth Sciences

Fingerprint' technique spots frog populations at risk from pollution

27.03.2017 | Life Sciences

Big data approach to predict protein structure

27.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>