Research at the University of York's Structural Biology Laboratory, in collaboration with groups in Canada, the USA and Sweden, has begun to uncover how our gut bacteria metabolise the complex dietary carbohydrates found in fruits and vegetables.
Trillions of bacteria live in human intestines - there are about ten times more bacterial cells in the average person's body than human ones. Known as "microbiota", these bacteria have a vital role to play in human health: they are central to our metabolism and well-being.
The research team has uncovered how one group of gut bacteria, known as Bacteroidetes, digest complex sugars known as xyloglucans. These make up to 25 per cent of the dry weight of dietary fruit and vegetables including lettuce, onion, aubergine and tomatoes.
Understanding how these bacteria digest complex carbohydrates informs studies on a wide range of nutritional issues. These include prebiotics (the consumption of 'beneficial' micro-organisms as a food supplement) and probiotics (the consumption of foods or supplements intended to stimulate the production of healthy bacteria in the gut).
Researchers from the York Structural Biology Laboratory in the University's Department of Chemistry, and international collaborators have carried out detailed structural and mechanistic studies into the precise functioning of specific enzymes. This work has shed further light on which organisms can and cannot digest certain fruits and vegetables, and how and why the "good bacteria" do what they do.
Professor Gideon Davies, who led the research at York, said: "Despite our omnivorous diet, humans aren't well equipped to eat complex plant matter; for this we rely on our gut bacteria. This work is helping us to understand the science of that process.
"The possible implications for commerce and industry extend beyond the realm of human nutrition, however. The study of how enzymes break down plant matter is also of direct relevance to the development of processes for environmentally-friendly energy solutions such as biofuels." The research at York was funded by the Biotechnology and Biological Sciences Research Council (BBSRC)
Caron Lett | EurekAlert!
Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy