Protein packaging may enhance MRI contrast.
Images of body tissues and organs could soon be brighter and sharper thanks to a technique developed by Italian chemists. They have made the chemical contrast agents used in magnetic resonance imaging (MRI) produce a stronger signal by trapping them in protein cages just 12 millionths of a millimetre (nanometres) or so widesup>1.
Such improvements increase the contrast of the images, so they should reveal more detailed information, enabling doctors to better discriminate between different tissue types. The researchers, Silvio Aime and co-workers at the University of Turin, hope to persuade their protein cages to latch onto particular cells, as this would help them to pinpoint diseased tissues.
PHILIP BALL | © Nature News Service
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