An aneurysm is a localised widening of an artery. It occurs because the artery wall is weakened and without treatment it could easily burst. If the aneurysm is in the aorta, the main artery that carries blood through the abdomen, the result often can be fatal. Doctors believe that any abdominal aortic aneurysm that is greater than 5cm is at a high risk of bursting.
To see whether a program of ultrasound screening could detect these aneurysms before they burst, and save lives as a result, Cochrane Researchers performed a systematic review of screening trials. They identified four controlled trials that were conducted in the UK, Denmark and Australia, and involved a total of 127,891 men and 9,342 women.
The results showed that men aged 65-79 could benefit from screening, but there were insufficient data on women (whose risk of death from ruptured aortic aneurysm is much lower than the risk in men) to ascertain effectiveness in women.
Understanding the nature of this benefit is complex. Screening detects aneurysms before they burst, and the opportunity to repair them early significantly reduced deaths from aortic aneurysms. However, not everyone with an aneurysm will die as a result, even if it is not repaired, and so some people whose aneurysm would not have otherwise burst are subjected to major surgery with its attendant complications or to anxiety about their unoperated aneurysm through screening. Screening had no significant effect on overall mortality, which is to be expected given that aortic aneurysm is relatively infrequent as a cause of death.
“The overall population benefit from screening appears to be established, in that fewer people died from their aortic aneurysm as a result of screening. However, there will still be some deaths and ill health resulting in a small number of people dying or suffering ill health as a result of elective aneurysm repair, who otherwise consider themselves healthy, and whose aneurysms detected by screening may not have ruptured in the future. Patients may therefore be asked to undergo risky surgery for a procedure that may not have killed them, others may discover small aneurysms and worry about them unnecessarily,” says lead author Dr Paul Cosford, Director of Public Health at the East of England Strategic Health Authority.
“Resource analysis indicates that screening may be cost effective in relatively developed countries, but that this needs further expert analysis particularly given the lack of information on life expectancy, complications of surgery or quality of life,” says Cosford. The researchers say there is a need to see whether surveying a larger population of women would demonstrate that they could benefit from screening as well.
Jennifer Beal | alfa
On track to heal leukaemia
18.01.2017 | Universitätsspital Bern
Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
18.01.2017 | Life Sciences
18.01.2017 | Information Technology
18.01.2017 | Life Sciences