Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Screening men over 65 for abdominal aortic aneurysms could save lives

16.05.2007
Between 5% and 10% of men aged 65 to 79 have abdominal aortic aneurysms, but don’t know it. If their weakened arteries burst they stand a very high risk of dying. Ultrasound screening of men in this age group can significantly reduce the numbers of men who die from this condition. The overall benefits of screening are complex, however, because many men may be subjected to unnecessary anxiety and/or to the complications of surgery.

An aneurysm is a localised widening of an artery. It occurs because the artery wall is weakened and without treatment it could easily burst. If the aneurysm is in the aorta, the main artery that carries blood through the abdomen, the result often can be fatal. Doctors believe that any abdominal aortic aneurysm that is greater than 5cm is at a high risk of bursting.

To see whether a program of ultrasound screening could detect these aneurysms before they burst, and save lives as a result, Cochrane Researchers performed a systematic review of screening trials. They identified four controlled trials that were conducted in the UK, Denmark and Australia, and involved a total of 127,891 men and 9,342 women.

The results showed that men aged 65-79 could benefit from screening, but there were insufficient data on women (whose risk of death from ruptured aortic aneurysm is much lower than the risk in men) to ascertain effectiveness in women.

Understanding the nature of this benefit is complex. Screening detects aneurysms before they burst, and the opportunity to repair them early significantly reduced deaths from aortic aneurysms. However, not everyone with an aneurysm will die as a result, even if it is not repaired, and so some people whose aneurysm would not have otherwise burst are subjected to major surgery with its attendant complications or to anxiety about their unoperated aneurysm through screening. Screening had no significant effect on overall mortality, which is to be expected given that aortic aneurysm is relatively infrequent as a cause of death.

“The overall population benefit from screening appears to be established, in that fewer people died from their aortic aneurysm as a result of screening. However, there will still be some deaths and ill health resulting in a small number of people dying or suffering ill health as a result of elective aneurysm repair, who otherwise consider themselves healthy, and whose aneurysms detected by screening may not have ruptured in the future. Patients may therefore be asked to undergo risky surgery for a procedure that may not have killed them, others may discover small aneurysms and worry about them unnecessarily,” says lead author Dr Paul Cosford, Director of Public Health at the East of England Strategic Health Authority.

“Resource analysis indicates that screening may be cost effective in relatively developed countries, but that this needs further expert analysis particularly given the lack of information on life expectancy, complications of surgery or quality of life,” says Cosford. The researchers say there is a need to see whether surveying a larger population of women would demonstrate that they could benefit from screening as well.

Jennifer Beal | alfa
Further information:
http://www.thecochranelibrary.com

More articles from Health and Medicine:

nachricht Researchers show p300 protein may suppress leukemia in MDS patients
28.03.2017 | University of Miami Miller School of Medicine

nachricht When writing interferes with hearing
28.03.2017 | Université de Genève

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Researchers create artificial materials atom-by-atom

28.03.2017 | Physics and Astronomy

Researchers show p300 protein may suppress leukemia in MDS patients

28.03.2017 | Health and Medicine

Asian dust providing key nutrients for California's giant sequoias

28.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>