This finding is supported by two papers published in this month’s BJS. Both pieces of research were led by Peter Holt, who works at St George’s Hospital, London.
“Our research adds to the evidence that concentrating surgical resources in large centres of excellence can provide great benefit to patients. A bad outcome in this type of surgery is death, and specialist centres are best placed to prevent it,” says Mr Holt.
An aortic aneurysm occurs when the muscle wall of the main artery that runs vertically through the body (the aortic artery) weakens and the artery bulges out irreversibly due to the blood pressure inside pushing out on the weakened segment. The wall can become extremely weak and the resulting bulge very large. If not repaired surgically, it is liable to tear (rupture) and cause catastrophic bleeding, which is fatal in 80% of cases as many patients never make it to a hospital.
The first paper reports an epidemiological study of UK data from 2000 to 2005 that investigated the outcomes of surgery on 112,545 patients. This showed that specialist centres dealing with more than 32 cases a year generate better outcomes than regional centres with lower caseloads. If the patient came in with a ruptured aneurysm the chance of survival was equally low in both regional and specialist centres.
The second paper reports a meta-analysis and systematic review that identified data, mainly from the USA, from 26 separate studies, which together involved over 350,000 patients. Peter Holt and his team concluded that a centre needed to be performing surgery on at least 43 abdominal aortic aneurysms before it could provide significantly greater chances of success. In this study, the benefit was present for non-ruptured and ruptured aneurysms alike.
“We believe that patients should be sent to centres that have a high volume of these cases and a proven track-record of high rates of success,” says Holt.
23.03.2017 | Technische Universität München
How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
23.03.2017 | Life Sciences
23.03.2017 | Power and Electrical Engineering
23.03.2017 | Earth Sciences