Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Expert develops nanoparticle drug delivery method to replace eye drops

28.09.2006
Eye drops could be a thing of the past thanks to an innovative and new method of delivering drugs to the eye using biodegradable materials.

This new method, developed by a team of researchers led by biomaterials and drug delivery expert Dr John Tsibouklis at the University of Portsmouth, uses biodegradable polymer nanoparticles to administer drugs to the eye.

Nanoparticles are microscopic particles measured in nanometres (nm). These particles are so small that an ant, for example, measures millions of nanometers across.

Dr Tsibouklis said biodegradable polymers can be combined with drugs in such a way that the drug is released into the eye in a very careful and controlled manner.

The drug would have to be placed into the eye just once.

'The drug's release can be timed so it is constant, cyclic or triggered by an environmental or chemical signal, and the drug delivering polymer can be broken down naturally by the body when it is no longer needed,' Dr Tsibouklis said.

People with eye conditions who use eye drops regularly would benefit from the biodegradable polymer drug delivery method.

Eye drops have many disadvantages – two main ones being the need to administer drops regularly and low ocular bioavailability (too little of the drug is getting to areas of the eye most in need).

The common alternative option to eye drops, ophthalmic inserts, achieve sustained drug delivery but suffer from limitations also – they are difficult to insert, easy to misapply, and are expensive to manufacture.

Dr Tsibouklis is a reader in polymer science at the University of Portsmouth’s School of Pharmacy and Biomedical Sciences.

Dr Tsibouklis, and colleagues Dr Eugen Barbu, Dr Tom Nevell and Dr Liliana Verestiuc describe the new drug delivery systems in a paper, titled ‘Polymeric materials for ophthalmic drug delivery: trends and perspectives', published in the Journal of Materials Chemistry.

He said that the new drug delivery systems hold significant promise for the pharmaceutical industry.

Rajiv Maharaj | alfa
Further information:
http://www.port.ac.uk

More articles from Health and Medicine:

nachricht New study points the way to therapy for rare cancer that targets the young
22.11.2017 | Rockefeller University

nachricht Penn study identifies new malaria parasites in wild bonobos
21.11.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Corporate coworking as a driver of innovation

22.11.2017 | Business and Finance

PPPL scientists deliver new high-resolution diagnostic to national laser facility

22.11.2017 | Physics and Astronomy

Quantum optics allows us to abandon expensive lasers in spectroscopy

22.11.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>