Study finds men with enlarged prostate can benefit from Botox injections
When researchers at the Chang Gung University Medical College, Taiwan and the University of Pittsburgh School of Medicine injected botulinum toxin A, or Botox, into the prostate gland of men with benign prostatic hyperplasia (BPH), a condition commonly referred to as enlarged prostate, they found that it eased symptoms and improved quality of life. Their results, based on 41 men with the condition, will be presented at the annual meeting of the American Urological Association (AUA) in Atlanta and published in abstract 1436 in the AUA proceedings.
"Millions of men in the United States suffer from enlarged prostate," said Michael B. Chancellor, M.D., professor of urology and gynecology at the University of Pittsburgh School of Medicine. "Its a challenging disease to live with because it causes frequent and difficult urination. Unfortunately, common treatments also are problematic because they carry some risk of serious side effects, such as impotence. Our results are encouraging because they indicate that Botox could represent a simple, safe and effective treatment for enlarged prostate."
Clare Collins | EurekAlert!
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Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
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