Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Not all breast cancers’ risk are increased by HRT

24.03.2006


Recent research presented today at EBCC-5 from the million women study found that taking Hormone Replacement Therapy (HRT) increased the risk of some types of breast cancer, but not others.



Scientists analysed the data from the UK study to try and find a link between HRT and the type of breast cancer that developed. The research found that women who took HRT had an increased risk of developing lobular cancer (affecting the cells in the ducts of the milk-producing glands) and tubular cancer. There was not such an increased risk of developing ductal breast cancer, the most common type of breast cancer that affects the cells lining the milk duct. There was no increase in the risk of medullary breast cancer, a kind of cancer that is common in women with a genetic predisposition to breast cancer.

The study demonstrated that women who had taken combined HRT (oestrogen and progesterone) had an even greater risk of developing lobular and tubular breast cancer than women on oestrogen only HRT. The researchers also discovered similar findings for women with breast cancer in situ - when the cancer has not spread to the surrounding tissues in the breast or other parts of the body. Women that took HRT had a significantly greater risk of developing lobular cancer in situ than ductal carcinoma in situ.


G. Reeves who presented the findings comments, "It is very interesting that HRT has different effects on different types of breast cancer. One possible explanation for the findings is that certain types of breast cancer are more likely than others to be hormone receptive. Further research into this topic could greatly help our understanding of the biological mechanisms underlying the development of breast cancer."

In 2003, the million women study confirmed that post-menopausal women taking combination HRT were twice as likely as non-users to develop breast cancer and women taking oestrogen-only HRT had a 30 per cent greater risk than those who haven’t taken HRT.

The increase in breast cancer risk starts within one to two years of beginning either form of HRT and increases the longer it is taken. As soon as HRT is stopped, the risk begins to fall and, after five years, is the same as for women who’ve never taken the drug. Combined oestrogen-progesterone HRT is usually prescribed for women who still have a uterus to avoid the increased risk of cancer of the uterus caused by oestrogen-only therapy. Women are advised to discuss their concerns with their doctor.

EBCC-5 Press Office | alfa
Further information:
http://www.fecs.be/emc.asp?pageId=616
http://www.cancerhelp.org.uk

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>