Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Not all breast cancers’ risk are increased by HRT

24.03.2006


Recent research presented today at EBCC-5 from the million women study found that taking Hormone Replacement Therapy (HRT) increased the risk of some types of breast cancer, but not others.



Scientists analysed the data from the UK study to try and find a link between HRT and the type of breast cancer that developed. The research found that women who took HRT had an increased risk of developing lobular cancer (affecting the cells in the ducts of the milk-producing glands) and tubular cancer. There was not such an increased risk of developing ductal breast cancer, the most common type of breast cancer that affects the cells lining the milk duct. There was no increase in the risk of medullary breast cancer, a kind of cancer that is common in women with a genetic predisposition to breast cancer.

The study demonstrated that women who had taken combined HRT (oestrogen and progesterone) had an even greater risk of developing lobular and tubular breast cancer than women on oestrogen only HRT. The researchers also discovered similar findings for women with breast cancer in situ - when the cancer has not spread to the surrounding tissues in the breast or other parts of the body. Women that took HRT had a significantly greater risk of developing lobular cancer in situ than ductal carcinoma in situ.


G. Reeves who presented the findings comments, "It is very interesting that HRT has different effects on different types of breast cancer. One possible explanation for the findings is that certain types of breast cancer are more likely than others to be hormone receptive. Further research into this topic could greatly help our understanding of the biological mechanisms underlying the development of breast cancer."

In 2003, the million women study confirmed that post-menopausal women taking combination HRT were twice as likely as non-users to develop breast cancer and women taking oestrogen-only HRT had a 30 per cent greater risk than those who haven’t taken HRT.

The increase in breast cancer risk starts within one to two years of beginning either form of HRT and increases the longer it is taken. As soon as HRT is stopped, the risk begins to fall and, after five years, is the same as for women who’ve never taken the drug. Combined oestrogen-progesterone HRT is usually prescribed for women who still have a uterus to avoid the increased risk of cancer of the uterus caused by oestrogen-only therapy. Women are advised to discuss their concerns with their doctor.

EBCC-5 Press Office | alfa
Further information:
http://www.fecs.be/emc.asp?pageId=616
http://www.cancerhelp.org.uk

More articles from Health and Medicine:

nachricht Vanishing capillaries
23.03.2017 | Technische Universität München

nachricht How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short

23.03.2017 | Life Sciences

Researchers use light to remotely control curvature of plastics

23.03.2017 | Power and Electrical Engineering

Sea ice extent sinks to record lows at both poles

23.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>