Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Grids to aid breast cancer diagnosis and research

08.12.2005


The millions of mammography exams performed each year in Europe save thousands of women’s lives, but if the data from all breast cancer screening procedures was made available to clinicians and researchers across the continent they could save many more. That is the vision behind MammoGrid.



The MammoGrid project is studying the commercial possibilities for its distributed computing environment that employs existing Grid technologies for the creation of a European database of mammogram data. By using Grid computing, the system allows hospitals, healthcare workers and researchers to share data and resources. It supports effective co-working, such as obtaining second opinions that reduce the risk of misdiagnosis, and opens the door to powerful statistical analysis of the incidence and forms of breast cancer to assist future research.

“Breast cancer is one of many diseases that is complicated to diagnose and for which Grid computing will prove to be a very valuable tool,” says Jean-Marie Le Goff, head of the Technology Transfer Service at CERN.


Breast cancer screening procedures suffer from several complications including the physical differences between the breasts of different women, the different procedures and equipment used to obtain mammography images, and the large amount of image data produced that makes computer-aided diagnosis (CAD) processing intensive.

These problems have contributed to the relatively high error rate of breast cancer screening procedures. It is estimated that around 30 per cent of mammograms result in either false positive diagnoses, whereby women are falsely diagnosed with breast cancer leading to unnecessary and painful biopsy, or, more seriously, in false negative diagnoses that lead to tumours going undetected.

With one in eight women developing breast cancer at some point in their lives and one in 28 dying from it, the importance of improving screening procedures and ensuring accurate diagnosis is evident.

By giving healthcare professionals the ability to use Grid computing to efficiently share data and resources their ability to accurately diagnose breast cancer is greatly enhanced. “A doctor in a small village, for example, probably doesn’t have access to powerful tools but with Grid computing he can provide the patient with an analysis from a hospital online. Also if cancer is detected the doctor would be able to monitor data from mammography exams taken over the course of months to determine the patient’s response to treatment,” notes Le Goff.

The interconnectivity the system provides between different hospitals and medical centres makes obtaining a second opinion simpler and faster, opening the door to tele-diagnosis and the creation of communities of medical ‘virtual organisations’ able to co-work using the shared resources of the Grid. Analysis of mammograms can be carried out in different locations using CAD tools, for example.

The resource-boosting properties of Grid computing are particularly important for creating a European distributed mammography database that would give healthcare professionals access to millions of mammography images to assist diagnosis and research.

Such a database would not only improve diagnosis through enhancing comparative analysis with other breast cancer cases, but would provide important statistical information about the epidemiology of the disease.

The project developed a proof-of-concept demonstrator to test their Grid architecture that so far allows access to 30,000 mammogram images. Grid boxes were set up and used by clinicians at hospitals in Cambridge in the United Kingdom and at Udine in Italy as well as by researchers at Oxford University with CERN acting as the central node.

The project’s success has led to interest from outside companies, with one Spanish firm, Helide, looking to deploy a commercial variant of the system in the region of Extremadura within a year.

“Helide is aiming to have a number of Grid boxes throughout the region that will enhance the ability of doctors to verify test results and obtain a second opinion and use of the clinical experience acquired by the Hospitals involved in the project. They then aim to scale it up in terms of what the system can do and the geographical area where it is used, expanding it to other areas of Spain and then Europe,” Le Goff says.

Tara Morris | alfa
Further information:
http://istresults.cordis.lu/

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>