Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Grids to aid breast cancer diagnosis and research

08.12.2005


The millions of mammography exams performed each year in Europe save thousands of women’s lives, but if the data from all breast cancer screening procedures was made available to clinicians and researchers across the continent they could save many more. That is the vision behind MammoGrid.



The MammoGrid project is studying the commercial possibilities for its distributed computing environment that employs existing Grid technologies for the creation of a European database of mammogram data. By using Grid computing, the system allows hospitals, healthcare workers and researchers to share data and resources. It supports effective co-working, such as obtaining second opinions that reduce the risk of misdiagnosis, and opens the door to powerful statistical analysis of the incidence and forms of breast cancer to assist future research.

“Breast cancer is one of many diseases that is complicated to diagnose and for which Grid computing will prove to be a very valuable tool,” says Jean-Marie Le Goff, head of the Technology Transfer Service at CERN.


Breast cancer screening procedures suffer from several complications including the physical differences between the breasts of different women, the different procedures and equipment used to obtain mammography images, and the large amount of image data produced that makes computer-aided diagnosis (CAD) processing intensive.

These problems have contributed to the relatively high error rate of breast cancer screening procedures. It is estimated that around 30 per cent of mammograms result in either false positive diagnoses, whereby women are falsely diagnosed with breast cancer leading to unnecessary and painful biopsy, or, more seriously, in false negative diagnoses that lead to tumours going undetected.

With one in eight women developing breast cancer at some point in their lives and one in 28 dying from it, the importance of improving screening procedures and ensuring accurate diagnosis is evident.

By giving healthcare professionals the ability to use Grid computing to efficiently share data and resources their ability to accurately diagnose breast cancer is greatly enhanced. “A doctor in a small village, for example, probably doesn’t have access to powerful tools but with Grid computing he can provide the patient with an analysis from a hospital online. Also if cancer is detected the doctor would be able to monitor data from mammography exams taken over the course of months to determine the patient’s response to treatment,” notes Le Goff.

The interconnectivity the system provides between different hospitals and medical centres makes obtaining a second opinion simpler and faster, opening the door to tele-diagnosis and the creation of communities of medical ‘virtual organisations’ able to co-work using the shared resources of the Grid. Analysis of mammograms can be carried out in different locations using CAD tools, for example.

The resource-boosting properties of Grid computing are particularly important for creating a European distributed mammography database that would give healthcare professionals access to millions of mammography images to assist diagnosis and research.

Such a database would not only improve diagnosis through enhancing comparative analysis with other breast cancer cases, but would provide important statistical information about the epidemiology of the disease.

The project developed a proof-of-concept demonstrator to test their Grid architecture that so far allows access to 30,000 mammogram images. Grid boxes were set up and used by clinicians at hospitals in Cambridge in the United Kingdom and at Udine in Italy as well as by researchers at Oxford University with CERN acting as the central node.

The project’s success has led to interest from outside companies, with one Spanish firm, Helide, looking to deploy a commercial variant of the system in the region of Extremadura within a year.

“Helide is aiming to have a number of Grid boxes throughout the region that will enhance the ability of doctors to verify test results and obtain a second opinion and use of the clinical experience acquired by the Hospitals involved in the project. They then aim to scale it up in terms of what the system can do and the geographical area where it is used, expanding it to other areas of Spain and then Europe,” Le Goff says.

Tara Morris | alfa
Further information:
http://istresults.cordis.lu/

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>