Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Drug Delivery to the Lungs exhibition in Edinburgh

08.11.2005


A new optical instrument that could vastly reduce the amount of time the pharmaceutical industry spends in R&D, by speeding up the measurement of drug inhaler performance, is being launched by Loughborough University spin out VariDose Limited.



Heightened interest in innovative pulmonary drug delivery is fuelled by the emergence of inhaled systemic drugs and global concern over the sharp rise in respiratory conditions such as asthma and chronic obstructive pulmonary disease. The groundbreaking product, VariDose, utilises custom-designed and state of the art opto-electronics and takes less than 60 seconds to run each test.

It enables drug delivery and pharmaceutical companies to quickly, and more efficiently, test a wide range of drug-device combinations at the development stage, without relying on standard inhaler testing methods.


The VariDose device provides additional valuable information on the detailed characteristics of the particle or droplet cloud emitted by the inhaler and can also be positioned in-line with other measurement devices, a breathing simulator or a patient.

VariDose works by measuring the cloud of drug released from an inhaler as it passes through a tube intersected by co-planar beams of red, blue and infra-red light. Sensors are able to monitor the structure of the evolving drug cloud as the light passes through. Detailed analysis is then presented on a standard Windows® enabled PC or laptop. Results can be used to investigate essential cloud characteristics related to variability in particle size distribution, fine particle fraction and dose to pinpoint how design modifications could improve both drug and device effectiveness.

"Current measurement systems, such as cascade impactors and impingers, have been around for over 20 years and are inflexible and labour intensive. The use of VariDose during R&D will dramatically increase the efficiency of the development process," says Peter Smith, Professor of Photonics at Loughborough University and co-inventor, of VariDose, with Dr Olga Kusmartseva.

"VariDose represents a major step change in novel device and drug formulation research by enabling companies to focus on effective drugs and devices," adds Brian Barney, head of Drug Delivery at Cambridge Consultants - who developed the complete product in just four months. He continues, "I’m confident that in years to come the industry could look back at this product as a defining innovation in the development of drugs and delivery methods."

VariDose will be launched at the Drug Delivery to the Lungs exhibition and conference in Edinburgh on 7 - 9 December 2005.

Anna Seddon | alfa
Further information:
http://www.lboro.ac.uk

More articles from Health and Medicine:

nachricht Satellites, airport visibility readings shed light on troops' exposure to air pollution
09.12.2016 | Veterans Affairs Research Communications

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>