Yale School of Medicine researchers have identified three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis (MS) patients, greatly improving potential diagnosis and treatment.
The team reports their findings in this weeks Proceedings of the National Academies of Science. MS is a crippling neurological disease resulting from damage to myelin insulation surrounding nerve fibers, and to nerve fibers themselves. MS symptoms can include muscle weakness or paralysis, loss of vision, loss of coordination, fatigue, pain and memory loss. There is currently no cure for MS. Existing medications and treatments help manage symptoms, slow down or modify disease progression.
Although anti-myelin antibodies are often found in MS patients, the diagnostic value of these molecules that respond to infection are limited because they are also found in patients without MS, making it difficult to determine their role in the development of the disease. In addition, MS patients might generate anti-myelin antibody responses that reflect, rather than cause, the disease.
Karen N. Peart | EurekAlert!
'Icebreaker' protein opens genome for t cell development, Penn researchers find
21.02.2018 | University of Pennsylvania School of Medicine
Similarities found in cancer initiation in kidney, liver, stomach, pancreas
21.02.2018 | Washington University School of Medicine
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
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