Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Remarkable enhancement of productivity for drugs through new real-time quality control


The Technical Research Centre of Finland, VTT has developed a new method, which increases product development cycle. This process will also enhance the competitiveness of drug development and reduce costs. VTT is working in collaboration with GlaxoSmithKline, GSK, one of the leading international pharmaceutical companies, to enhance quality control for drugs by using Process Analytical Technologies (PAT). The goal of the PAT is to develop drug process’ production analysis into real-time quality control and to decrease significantly production costs.

VTT’s optical measurement methods, in drug production, will help pharmaceutical companies increase the quality and safety of their products. Manufacturing cost of drugs play an important role in the cost of pharmaceutical products, as 40% of the price is coming from production.

One of the major problems in developing drug manufacturing processes is the lack of fast and reliable measurement techniques. At the moment, the quality measurement technique consists mainly of slow laboratory analyses, which do not enable real-time quality control. The effective manufacturing of a drug takes only one to two days whereas in practice the whole manufacturing process may take as long as 30-60 days.

VTT has one of the world’s largest groups of specialists, totally 45 man-years annual volume, developing on new process measurement equipment. At the moment, VTT has developed state-of-art optical instrumentation mainly for other process industries such as pulp&paper and metal. In this project the challenge is to transfer and utilize this Finnish process measurement knowledge to the pharmaceutical processes. VTT will collaborate with GSK to improve GSK drug manufacturing processes by using the high-tech PAT technologies.

VTT and GSK assignment is significant for VTT as the two -year project is worth up to 1.5 million Euro. The main target of this project is to create and develop new innovative measurement systems and business opportunities to Finnish measurement and sensor companies. Measurement systems will be tested in several production lines including GSK plants in UK, Italy, Spain and Canada.

Finnish industry has been to the forefront in developing strong industrial process understanding, strongly supported by the collaborative R&D work undertaken by renowned institutes such as VTT. The various R&D programs have been coordinated, advised and supported by Tekes, the Finnish national technology agency, whose strategy is to develop new international links for Finnish technology abroad.

Irene Hernberg | alfa
Further information:

More articles from Health and Medicine:

nachricht Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection
24.10.2016 | Universität Basel

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Ice shelf vibrations cause unusual waves in Antarctic atmosphere

25.10.2016 | Earth Sciences

Fluorescent holography: Upending the world of biological imaging

25.10.2016 | Power and Electrical Engineering

Etching Microstructures with Lasers

25.10.2016 | Process Engineering

More VideoLinks >>>