“Positron Emission Topography with choline demonstrates greater efficiency in the early diagnosis of relapsed prostate cancer with respect to other imaging techniques”, stated Dr. Macarena Rodríguez, of the Nuclear Medicine Service at the University Hospital of the University of Navarra. She was speaking on receiving the award for the best scientific work at the XXVI National Congress of the Spanish Society for Nuclear Medicine (SEMN), held recently in Maspalomas (the Canary Islands).
The study, entitled, “Value of PET with FDG and 11C-Choline in early diagnosis of relapsed treated prostate carcinoma”, has analysed for the first time in Spain the utility of 11C-Choline for the detection of relapses in these tumours. To date, conventional FDG (F18-fluorodeoxyglucose) has been used as a radiopharmaceutical, offering good specificity but poor sensitivity in the diagnosis of relapsed prostate carcinoma. The research centred on the analysis of the role of the choline and compared it with the results using FDG.
The research, carried out with 38 patients at the Navarre University Hospital, found that 11C-Choline gives better results in diagnosing relapsed prostate cancer. Although both radiopharmaceuticals have a specificity and a predictive negative value of 100%, 11C-Choline shows a sensitivity of 65% in the detection of relapses with low PSA (prostate-specific antigen) level, compared to 28% of FDG. Thus, it is shown to be a radiopharmaceutical especially useful for the early detection of relapsed prostate carcinoma. What is needed now are more studies to enable comparison of its results in function of the treatment that primary tumours require - radiotherapy, surgery, etc.
Garazi Andonegi | alfa
Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania
The strange double life of Dab2
10.01.2017 | University of Miami Miller School of Medicine
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
17.01.2017 | Earth Sciences
17.01.2017 | Materials Sciences
17.01.2017 | Architecture and Construction