“Positron Emission Topography with choline demonstrates greater efficiency in the early diagnosis of relapsed prostate cancer with respect to other imaging techniques”, stated Dr. Macarena Rodríguez, of the Nuclear Medicine Service at the University Hospital of the University of Navarra. She was speaking on receiving the award for the best scientific work at the XXVI National Congress of the Spanish Society for Nuclear Medicine (SEMN), held recently in Maspalomas (the Canary Islands).
The study, entitled, “Value of PET with FDG and 11C-Choline in early diagnosis of relapsed treated prostate carcinoma”, has analysed for the first time in Spain the utility of 11C-Choline for the detection of relapses in these tumours. To date, conventional FDG (F18-fluorodeoxyglucose) has been used as a radiopharmaceutical, offering good specificity but poor sensitivity in the diagnosis of relapsed prostate carcinoma. The research centred on the analysis of the role of the choline and compared it with the results using FDG.
The research, carried out with 38 patients at the Navarre University Hospital, found that 11C-Choline gives better results in diagnosing relapsed prostate cancer. Although both radiopharmaceuticals have a specificity and a predictive negative value of 100%, 11C-Choline shows a sensitivity of 65% in the detection of relapses with low PSA (prostate-specific antigen) level, compared to 28% of FDG. Thus, it is shown to be a radiopharmaceutical especially useful for the early detection of relapsed prostate carcinoma. What is needed now are more studies to enable comparison of its results in function of the treatment that primary tumours require - radiotherapy, surgery, etc.
Garazi Andonegi | alfa
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Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
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In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
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