Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Largest Diet and Exercise Trial in the World for Type 2 Diabetes


A massive grant of almost a million pounds has been awarded to the University of Bristol to carry out a major trial that will assess the effects of diet and exercise on people with type 2 diabetes. This trial will be the largest diet and exercise trial in the world for people with type 2 diabetes.

The recent large rise in the number of people suffering from type 2 diabetes is closely linked to the increase in obesity within the population, and this is thought to be due to a lack of exercise and an increase in food intake. Although we know a lot about how diet can control glucose levels and improve blood pressure and cholesterol, very little is known about how, or if, exercise affects these factors. This study aims to definitively answer these questions for the first time.

Dr Robert Andrews from the University of Bristol, who will lead the trial, said: “This is the largest exercise trial to be conducted in this country, and the largest exercise trial in the world for people with type 2 diabetes. We feel it will be a land mark trial from which crucial information on long-term glucose control, insulin sensitivity, insulin resistance, weight and blood pressure will emerge, allowing us to compare the effects of these conditions in each of the groups”.

The trial aims to recruit 750 people from across the Southwest who have been newly diagnosed with type 2 diabetes. Individuals will be allocated to one of three groups. Those in the first group will receive regular help and advice on improving their diet, the second group will receive the same dietary advice, but in addition they will receive help to increase their daily levels of exercise. The control group will receive the usual care.

Dr Ashley Cooper, also from the University of Bristol, said: “Participants in the exercise group will wear activity monitors all day every day. As they walk around and go about their daily business, these instruments will monitor just how many calories they are burning. Participants will be set targets to aim for so that they gradually increase the amount of exercise they do”.

Individuals will be recruited onto the trial within five months of being diagnosed and will remain in the trial for a year. The trial itself will run for three years.

Type 2 diabetes, previously known as ‘adult-onset diabetes’, commonly starts in adulthood, after the age of 30. In the last 30 years the number of people with type 2 diabetes has trebled and a further trebling in the number of patients is expected in the next ten years. This huge rise is closely linked to the recent increase in obesity within the population and threatens to be a major health problem in the future, if people cannot be persuaded to change their life styles.

Diabetes is a condition where the body can no longer control its blood sugar level. Without adequate control the level tends to rise dramatically and remains high. Over time, these high levels can result in damage to blood vessels leading to heart disease, stroke, blindness, kidney failure, impotence, circulatory problems and nerve damage.

The trial will be launched in November 2004. ‘Education days’ will be set up and doctors’ surgeries across the Southwest, from Gloucester to Taunton, will be able to refer patients newly diagnosed with type 2 diabetes to an education day. Patients attending these days will be given information about the study and be offered the opportunity to enter the trial.

The programme is a joint study between three departments at the University of Bristol. Drs Robert Andrews and Ashley Cooper in the Department of Exercise and Health Sciences, Dr Colin Dayan from Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, and Dr Alan Montgomery and Professors Tim Peters and Debbie Sharp in Primary Health Care. The grant from Diabetes UK (£240,000) is supported by a further £680,000 from the Department of Health.

| newswise
Further information:

More articles from Health and Medicine:

nachricht Advanced analysis of brain structure shape may track progression to Alzheimer's disease
26.10.2016 | Massachusetts General Hospital

nachricht Indian roadside refuse fires produce toxic rainbow
26.10.2016 | Duke University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

How nanoscience will improve our health and lives in the coming years

27.10.2016 | Materials Sciences

OU-led team discovers rare, newborn tri-star system using ALMA

27.10.2016 | Physics and Astronomy

'Neighbor maps' reveal the genome's 3-D shape

27.10.2016 | Life Sciences

More VideoLinks >>>