Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Largest Diet and Exercise Trial in the World for Type 2 Diabetes

27.07.2004


A massive grant of almost a million pounds has been awarded to the University of Bristol to carry out a major trial that will assess the effects of diet and exercise on people with type 2 diabetes. This trial will be the largest diet and exercise trial in the world for people with type 2 diabetes.



The recent large rise in the number of people suffering from type 2 diabetes is closely linked to the increase in obesity within the population, and this is thought to be due to a lack of exercise and an increase in food intake. Although we know a lot about how diet can control glucose levels and improve blood pressure and cholesterol, very little is known about how, or if, exercise affects these factors. This study aims to definitively answer these questions for the first time.

Dr Robert Andrews from the University of Bristol, who will lead the trial, said: “This is the largest exercise trial to be conducted in this country, and the largest exercise trial in the world for people with type 2 diabetes. We feel it will be a land mark trial from which crucial information on long-term glucose control, insulin sensitivity, insulin resistance, weight and blood pressure will emerge, allowing us to compare the effects of these conditions in each of the groups”.


The trial aims to recruit 750 people from across the Southwest who have been newly diagnosed with type 2 diabetes. Individuals will be allocated to one of three groups. Those in the first group will receive regular help and advice on improving their diet, the second group will receive the same dietary advice, but in addition they will receive help to increase their daily levels of exercise. The control group will receive the usual care.

Dr Ashley Cooper, also from the University of Bristol, said: “Participants in the exercise group will wear activity monitors all day every day. As they walk around and go about their daily business, these instruments will monitor just how many calories they are burning. Participants will be set targets to aim for so that they gradually increase the amount of exercise they do”.

Individuals will be recruited onto the trial within five months of being diagnosed and will remain in the trial for a year. The trial itself will run for three years.

Type 2 diabetes, previously known as ‘adult-onset diabetes’, commonly starts in adulthood, after the age of 30. In the last 30 years the number of people with type 2 diabetes has trebled and a further trebling in the number of patients is expected in the next ten years. This huge rise is closely linked to the recent increase in obesity within the population and threatens to be a major health problem in the future, if people cannot be persuaded to change their life styles.

Diabetes is a condition where the body can no longer control its blood sugar level. Without adequate control the level tends to rise dramatically and remains high. Over time, these high levels can result in damage to blood vessels leading to heart disease, stroke, blindness, kidney failure, impotence, circulatory problems and nerve damage.

The trial will be launched in November 2004. ‘Education days’ will be set up and doctors’ surgeries across the Southwest, from Gloucester to Taunton, will be able to refer patients newly diagnosed with type 2 diabetes to an education day. Patients attending these days will be given information about the study and be offered the opportunity to enter the trial.

The programme is a joint study between three departments at the University of Bristol. Drs Robert Andrews and Ashley Cooper in the Department of Exercise and Health Sciences, Dr Colin Dayan from Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, and Dr Alan Montgomery and Professors Tim Peters and Debbie Sharp in Primary Health Care. The grant from Diabetes UK (£240,000) is supported by a further £680,000 from the Department of Health.

| newswise
Further information:
http://www.bris.ac.uk

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>