A study just completed by researchers at the Josephine Ford Cancer Center has resulted in the most comprehensive long-term prostate cancer survival model available to date. An interactive version of the survival model is available online at prostatecalculator.org. Patients and doctors who visit the site can obtain a personalized 10-year survival estimate based on age, race, a few clinical measures, and the kind of treatment being pursued. Once data have been entered, a simple mouse-click provides the prognosis.
Dr. Ashutosh Tewari, with the Josephine Ford Cancer Center (Detroit, MI) worked with investigators at ANNs in CaP (Denver, CO) to retrospectively identify a cohort of 1,611 patients with clinically localized prostate cancer as well as 4,538 age, race, and co-morbidity (those with additional diseases) matched controls. Based on demographic and clinical variables, propensity risk scoring was used to develop survival probability estimates for both patients and controls. Because the calculator, and the companion look-up tables published in the April issue of the Journal of Urology, provide a comparison with men with similar characteristics but who do not have prostate cancer, users receive a realistic estimate of the impact of prostate cancer on long-term survival.
Prostate cancer is the most common solid-organ male malignancy diagnosed in the United States, with an estimated 189,000 new cases each year. Currently, African-American men have the highest incidence of prostate cancer in the world (137 per 100,000 per year), and are 2.5 times as likely to die as whites. While the reason for this is not known, some research suggests that black men are often diagnosed at later disease stages. Dr. Tewari adds, "Our research indicates that African-American men also tend to undergo less aggressive treatment than whites, and additional studies by our group suggest that if they received the same treatments, their prostate cancer survival rates would be much closer to those of whites." The study also showed that a man’s level of co-morbidities can have as much or more of an impact on his chances of long-term survival than his prostate cancer alone.
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
27.02.2017 | Materials Sciences
27.02.2017 | Interdisciplinary Research
27.02.2017 | Life Sciences