Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Earlier diagnosis of schizophrenia improves results of treatment

27.02.2004


Detecting and treating schizophrenia rapidly, following the onset of a first psychotic episode, improves the patients’ response to treatment, according to a study by a Yale researcher.



Thomas McGlashan, M.D., professor of psychiatry at Yale School of Medicine, said the length of time between the onset of psychosis and detection and treatment can stretch from several weeks to several years. This time span is a concern because the patient is sick and untreated and because there is some indication that the untreated psychotic state itself may increase the risk of a poor outcome.

"It looks like the longer the period of time before treatment, the worse off the patients are not only when they come into treatment, but how they respond to treatment," McGlashan said.


In a study published this month in the Archives of General Psychiatry, McGlashan looked at 281 patients in four Scandanavian health sectors with equivalent treatment programs. Two of the four sectors had early detection programs and two did not. Those that did have programs educated residents, school counselors, and health care workers about psychotic symptoms such as increasing isolation, responding to voices no one else hears, delusional thinking, irritability, difficulty sleeping, and overall marked reduction in the ability to cope with life’s daily stresses.

Participants were followed up after three months, one year and two years. This study compares the patients’ clinical state at admission and at the three month follow up. The researchers found that the duration of untreated patient psychosis in the two health sectors with early detection programs was significantly shorter -- one month as compared to four months.

"All factors being equal, early detection efforts will bring people into treatment at lower symptom levels," McGlashan said. "Patients who began treatment earlier tended to be younger, less symptomatic, and more responsive to treatment."

He said there will be a follow up after one, two , five and 10 years to see if the early detection and intervention has a lasting effect.


Co-authors included Ingrid Melle, M.D., Svein Friis, M.D., Stein Opjordsmoen, M.D., Bjorn Roshovd Rund, Per Vaglum, M.D., Tor Larsen, M.D., Jan Olav Johannessen, M.D., Ulrik Haahr, M.D., and Erik Simonsen, M.D.

Citation: Archives of General Psychiatry, 61:143-150.

Jacqueline Weaver | EurekAlert!
Further information:
http://www.yale.edu/

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>