New dressing for wound developed at Hebrew University promises faster and improved healing
A novel wound dressing made of genetically engineered human collagen that will enable faster and improved healing of injuries has been developed by researchers at the Hebrew University Faculty of Dental Medicine.
Prof. Shmuel Shoshan
Collagen is the most abundant protein in the animal kingdom, including humans. It is the major constituent of connective tissues – tendons, skin, bones, cartilage, blood vessel walls and membranes. Collagen fibers are the “warp and woof” of these connective tissues and are responsible for keeping all the body’s organs and tissues in their correct functional structure.
There are different collagen-containing preparations on the market today made for treating wounds, for use in dentistry implants, and in cosmetics. All of them use collagen made from animal tissues, which requires specific adaptation in order to eliminate immunological rejection or to prevent microbiological infection.
The dressing developed at the Hebrew University incorporates an inner layer of genetically engineered, human recombinant collagen. This material becomes a soluble, readily enzymatically degradable molecule in the wound tissue. The molecular fragments that are thus formed have been shown to play a pivotal role in the healing process. An outer layer, also of biological origin, is provided in the wound dressing to provide initial protection prior to release of the delicate collagen layer.
Preliminary animal experiments with the new dressing have shown substantially faster and better healing, with rapid formation of new collagen fibers, than has been possible using older methods.
The new dressing is the fruit of many years of experimentation with collagen in the laboratory of Prof. Emeritus Shmuel Shoshan of the Connective Tissue Research Laboratory of the Hebrew University Faculty of Dental Medicine. Prof. Shoshan is the inventor and chief scientist of Dittekol Ltd., a company formed in cooperation with the Hebrew University’s Yissum Research Development Company, to commercialize the new wound dressing. The company is now negotiating with investors for further development.
For further information: Jerry Barach, Dept. of Media Relations, the Hebrew University, Tel: 02-588-2904
Jerry Barach | Hebrew University
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.
Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...