Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Hope For New Meningitis Vaccine

05.01.2004


Research performed by scientists at the School of Biomedical and Molecular Sciences, University of Surrey and the Health Protection Agency (Porton Down, Salisbury) provides hope for developing a new meningitis vaccine that will protect children against all groups of meningococcus.



Published in the journal, Infection and Immunity, the research found that meningococcus is responsible for epidemics of meningitis worldwide that kills thousands of children each year. Vaccines are available for the A and C groups, but no effective vaccine is currently available for B groups. There are about 1500 confirmed cases of group B meningitis in the UK each year, but the true incidence is likely to be nearer twice that number since many cases go unreported. About 10% of children who suffer meningococcal meningitis die of the disease and many of the survivors are left severely handicapped.

The Surrey researchers used genetic engineering technology to make a mutant group of the meningococcus that was incapable of causing disease in mice. The mutant was made in a C group of the meningococcus. However, mice that were inoculated with the mutant group developed antibodies that killed not only C groups but also B and A groups. It appears that, by inoculating with the disabled group, the mice have effectively been immunised against all groups.


The research suggests that it should be possible to develop a single vaccine to protect against all groups of the meningococcus. Such a vaccine could revolutionise meningitis vaccination around the world. The researchers are now analysing the immune response of the immunised mice to try and discover the identity of the targets that the mouse antibodies are hitting.

Although much work needs to be done, the research holds real promise that a new vaccine may be developed that will protect children against all groups of the meningococcus, both in the UK and around the world.

The research is supported by the Meningitis Trust.

Liezel Tipper | alfa
Further information:
http://www.surrey.ac.uk

More articles from Health and Medicine:

nachricht New vaccine production could improve flu shot accuracy
25.07.2017 | Duke University

nachricht Chances to treat childhood dementia
24.07.2017 | Julius-Maximilians-Universität Würzburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA mission surfs through waves in space to understand space weather

25.07.2017 | Physics and Astronomy

Strength of tectonic plates may explain shape of the Tibetan Plateau, study finds

25.07.2017 | Earth Sciences

The dense vessel network regulates formation of thrombocytes in the bone marrow

25.07.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>