Researchers from Germany have identified a gene that is associated with an increased risk of suffering from skin cancer. The research, published this month in Journal of Carcinogenesis, could also explain why men are more likely to suffer from malignant melanoma than women.
Although most people associate melanoma with exposure to UV light, through excessive sunbathing for example, the disease can be inherited – indicating that faulty genes are also partly to blame. Genetic risk factors also affect the likelihood of individuals suffering from non-inherited, or sporadic, melanoma.
To identify these risk factors, researchers from the University Hospital in Tuebingen took blood samples from 450 healthy volunteers, and 500 people who had been diagnosed with malignant melanoma, from which they could extract DNA. In collaboration with Genefinder Technologies Ltd., Munich, Germany and Sequenom Inc., San Diego, USA, the researchers studied the DNA samples, looking for slight differences in the genes between people with melanoma skin cancer and people with no cancers at all. To do this they screened more than 25,000 sites across the whole genome, which are known to vary naturally between different people.
Gemma Bradley | BioMed Central
Fast-tracking T cell therapies with immune-mimicking biomaterials
16.01.2018 | Wyss Institute for Biologically Inspired Engineering at Harvard
Dengue takes low and slow approach to replication
12.01.2018 | Duke University
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
16.01.2018 | Materials Sciences
16.01.2018 | Life Sciences
16.01.2018 | Health and Medicine