Post-operative chemotherapy in non-small cell lung cancer (NSCLC) looks like an attractive proposition to prevent the cancer recurring, said Professor Nick Thatcher, of the Christie Hospital, Manchester, UK at the ECCO-12 conference in Copenhagen today (Tuesday 23 September). But the recent IALT study, which is said to demonstrate a survival advantage for patients given adjuvant treatment, was statistically unreliable and needed to be taken in context, he said.
"A large body of evidence – 17 cisplatin trials as opposed to 1, the IALT study -demonstrated no survival advantage with the use of cisplatin-based adjuvant chemotherapy", said Professor Thatcher.
A meta-analysis of 14 trials of adjuvant (post resection cisplatin therapy) in NSCLC not only showed no survival benefit with chemotherapy, said Professor Thatcher, but with adjuvant radiotherapy (which was included in the IALT study) there was a survival detriment, 7% more people treated dying over 2 years. Three other more recent randomised cisplatin trials had also failed to show a survival benefit among patients receiving adjuvant chemotherapy in NSCLC, he said.
Mary Rice | EurekAlert!
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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