Tamoxifen appears to reduce the risk of benign breast disease and may result in fewer biopsies, according to an analysis of data from a major randomized clinical trial of tamoxifen. The findings appear in the February 19 issue of the Journal of the National Cancer Institute.
Tamoxifen was shown in the Breast Cancer Prevention Trial to reduce the incidence of invasive and noninvasive breast cancer by as much as 50% compared to placebo. Other studies have suggested that tamoxifen can also decrease the size of benign breast lesions, which have been associated with a modest increase in the risk for developing invasive breast cancer.
To examine the effect of tamoxifen on the risk of developing benign breast lesions, Elizabeth Tan-Chiu, M.D., of the Cancer Research Network in Plantation, Fla., and her coworkers from the National Surgical Adjuvant Breast and Bowel Project examined the incidence of benign breast disease among 13,203 women treated with either tamoxifen or a placebo as part of the Breast Cancer Prevention Trial. The authors also noted how many biopsies each group of women underwent.
Linda Wang | EurekAlert!
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Disrupted fat breakdown in the brain makes mice dumb
19.05.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...
For the first time, scientists have succeeded in studying the strength of hydrogen bonds in a single molecule using an atomic force microscope. Researchers from the University of Basel’s Swiss Nanoscience Institute network have reported the results in the journal Science Advances.
Hydrogen is the most common element in the universe and is an integral part of almost all organic compounds. Molecules and sections of macromolecules are...
22.05.2017 | Event News
17.05.2017 | Event News
16.05.2017 | Event News
22.05.2017 | Materials Sciences
22.05.2017 | Life Sciences
22.05.2017 | Physics and Astronomy