Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fish fat kills cancer cells

14.10.2002


Fatty acids from fish oils and fatty fish can destroy the power station - the mitochondria- in certain types of cancer cells, making the cells commit suicide.These are the conclusions in a new thesis that Hilde Heimli at the Institute for Nutrition Research at the University of Oslo, in Norway, presented in October 2002. The study was supported by the Norwegian Cancer Society.



Kreft.no: In her thesis, Hilde Heimli has examined how polyunsaturated omega-3 fatty acid is ingested by different leukemia/lymphoma cell lines. The researcher has examined how some types of cancer cells commit suicide in this setting, in other words programmed cell death or apoptosis.

Activated by an enzyme
If omega-3 fatty acids are to be capable of killing cancer cells, the cells have to contain a certain enzyme, that activate these certain fatty acids. Cancer cells that contain less of this enzyme do not react to fish fat.



"Polyunsaturated fatty acids from fish also can initiate a less regulated cell death called necrosis. The reason for the necrotic cell death is an increased production of reactive oxygen species in the cells. It is possible to appose this necrosis by the presence of antioxidants such as Vitamin C and E," says Hilde Heimli to www.kreft.no

Can prevent cancer
This work contributes to an increased understanding of how cancer cells grow and develop. This knowledge may play an important role in the prevention and treatment of certain types of cancer. Heimli’s experiments are developed from cancer cell lines – cells that originally came from leukemia patients,but she doesn’t see any reason that cancer cells of other origins shouldn’t commit suicide when exposed to fish fat.

So far - laboratory experiments
"The experiments have been done in dishes in a laboratory setting. The polyunsaturated fatty acids that are used are eicosapentaenoic acid (EPA),which are the same type as found in fatty fish or regular fish oil capsules.

The fatty acids are added to the the food given to the cancer cells in a way that is most like the body’s own process," says Heimli.

The basic knowledge from this work contributes to a larger understanding of growth regulation in cancer cells.

As a final result, one believes that this new knowledge can be used in the prevention and treatment of certain types of cancer.


Questions?
If you have any questions, please contact the editorial office:
redaksjonen@kreft.no

Barbara Mortensen | EurekAlert!

More articles from Health and Medicine:

nachricht The end of pneumonia? New vaccine offers hope
23.10.2017 | University at Buffalo

nachricht Scientists track ovarian cancers to site of origin: Fallopian tubes
23.10.2017 | Johns Hopkins Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Salmonella as a tumour medication

HZI researchers developed a bacterial strain that can be used in cancer therapy

Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

3rd Symposium on Driving Simulation

23.10.2017 | Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

 
Latest News

Microfluidics probe 'cholesterol' of the oil industry

23.10.2017 | Life Sciences

Gamma rays will reach beyond the limits of light

23.10.2017 | Physics and Astronomy

The end of pneumonia? New vaccine offers hope

23.10.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>