Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fish fat kills cancer cells

14.10.2002


Fatty acids from fish oils and fatty fish can destroy the power station - the mitochondria- in certain types of cancer cells, making the cells commit suicide.These are the conclusions in a new thesis that Hilde Heimli at the Institute for Nutrition Research at the University of Oslo, in Norway, presented in October 2002. The study was supported by the Norwegian Cancer Society.



Kreft.no: In her thesis, Hilde Heimli has examined how polyunsaturated omega-3 fatty acid is ingested by different leukemia/lymphoma cell lines. The researcher has examined how some types of cancer cells commit suicide in this setting, in other words programmed cell death or apoptosis.

Activated by an enzyme
If omega-3 fatty acids are to be capable of killing cancer cells, the cells have to contain a certain enzyme, that activate these certain fatty acids. Cancer cells that contain less of this enzyme do not react to fish fat.



"Polyunsaturated fatty acids from fish also can initiate a less regulated cell death called necrosis. The reason for the necrotic cell death is an increased production of reactive oxygen species in the cells. It is possible to appose this necrosis by the presence of antioxidants such as Vitamin C and E," says Hilde Heimli to www.kreft.no

Can prevent cancer
This work contributes to an increased understanding of how cancer cells grow and develop. This knowledge may play an important role in the prevention and treatment of certain types of cancer. Heimli’s experiments are developed from cancer cell lines – cells that originally came from leukemia patients,but she doesn’t see any reason that cancer cells of other origins shouldn’t commit suicide when exposed to fish fat.

So far - laboratory experiments
"The experiments have been done in dishes in a laboratory setting. The polyunsaturated fatty acids that are used are eicosapentaenoic acid (EPA),which are the same type as found in fatty fish or regular fish oil capsules.

The fatty acids are added to the the food given to the cancer cells in a way that is most like the body’s own process," says Heimli.

The basic knowledge from this work contributes to a larger understanding of growth regulation in cancer cells.

As a final result, one believes that this new knowledge can be used in the prevention and treatment of certain types of cancer.


Questions?
If you have any questions, please contact the editorial office:
redaksjonen@kreft.no

Barbara Mortensen | EurekAlert!

More articles from Health and Medicine:

nachricht Finnish research group discovers a new immune system regulator
23.02.2018 | University of Turku

nachricht Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Attoseconds break into atomic interior

A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.

In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...

Im Focus: Good vibrations feel the force

A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.

By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...

Im Focus: Developing reliable quantum computers

International research team makes important step on the path to solving certification problems

Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Basque researchers turn light upside down

23.02.2018 | Physics and Astronomy

Finnish research group discovers a new immune system regulator

23.02.2018 | Health and Medicine

Attoseconds break into atomic interior

23.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>